Simplified within-host and dose-response models of SARS-CoV-2

DOI10.1016/J.JTBI.2023.111447MaRDI QIDQ6174192zbMATH OpenFDO

Authors Jingsi Xu, Jonathan Carruthers, Thomas Finnie, Ian M. Hall

Publication date 14 July 2023

Published in Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/J.JTBI.2023.111447

zbMATH Keywords

dose-responseSARS-CoV-2within-host models

Mathematics Subject Classification ID

Epidemiology (92D30)

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Cites work

• scientific article; zbMATH DE number 3863589 (Why is no real title available?)
• Modeling amantadine treatment of influenza A virus in vitro
• Modeling the viral dynamics of SARS-CoV-2 infection

Cited in

(12)

• The within-host viral kinetics of SARS-CoV-2
• A model for SARS-CoV-2 infection with treatment
• A simple in-host model for COVID-19 with treatments: model prediction and calibration
• Relationship between the inclusion/exclusion criteria and sample size in randomized controlled trials for SARS-CoV-2 entry inhibitors
• Why, when and how should exposure be considered at the within-host scale? A modelling contribution to PRRSv infection
• A mathematical model of within-host COVID-19 dynamics
• Modelling how increased Cathepsin B/L and decreased TMPRSS2 usage for cell entry by the SARS-CoV-2 Omicron variant may affect the efficacy and synergy of TMPRSS2 and Cathepsin B/L inhibitors
• Multiple cohort study of hospitalized SARS-CoV-2 in-host infection dynamics: parameter estimates, identifiability, sensitivity and the eclipse phase profile
• Modeling identifies variability in SARS-CoV-2 uptake and eclipse phase by infected cells as principal drivers of extreme variability in nasal viral load in the 48 h post infection
• A mechanistic modeling and estimation framework for environmental pathogen surveillance
• Impact of heterogeneity on infection probability: insights from single-hit dose-response models
• From trait-structured within-host dynamics to SIR models: a multiscale framework with re-exposure

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