The sequential rejection principle of familywise error control
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Abstract: Closed testing and partitioning are recognized as fundamental principles of familywise error control. In this paper, we argue that sequential rejection can be considered equally fundamental as a general principle of multiple testing. We present a general sequentially rejective multiple testing procedure and show that many well-known familywise error controlling methods can be constructed as special cases of this procedure, among which are the procedures of Holm, Shaffer and Hochberg, parallel and serial gatekeeping procedures, modern procedures for multiple testing in graphs, resampling-based multiple testing procedures and even the closed testing and partitioning procedures themselves. We also give a general proof that sequentially rejective multiple testing procedures strongly control the familywise error if they fulfill simple criteria of monotonicity of the critical values and a limited form of weak familywise error control in each single step. The sequential rejection principle gives a novel theoretical perspective on many well-known multiple testing procedures, emphasizing the sequential aspect. Its main practical usefulness is for the development of multiple testing procedures for null hypotheses, possibly logically related, that are structured in a graph. We illustrate this by presenting a uniform improvement of a recently published procedure.
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Cites work
- scientific article; zbMATH DE number 3624650 (Why is no real title available?)
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- Resampling-based multiple testing for microarray data analysis (With comments)
- Some probability inequalities for ordered MTP₂ random variables: a proof of the Simes conjecture
- Testing Statistical Hypotheses
- Testing hypotheses in order
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Cited in
(39)- Multiple testing for exploratory research
- Hierarchical inference for genome-wide association studies: a view on methodology with software
- Goodness-of-Fit Testing for the Newcomb-Benford Law With Application to the Detection of Customs Fraud
- Shortcuts for locally consonant closed test procedures
- \(F\)-distribution calibrated empirical likelihood ratio tests for multiple hypothesis testing
- Multiple testing along a tree
- Discussion on “Testing small study effects in multivariate meta‐analysis” by Chuan Hong, Georgia Salanti, Sally Morton, Richard Riley, Haitao Chu, Stephen E. Kimmel and Yong Chen
- Assessing the pattern of covariance matrices via an augmentation multiple testing procedure
- A multiple testing method for hypotheses structured in a directed acyclic graph
- The union closure method for testing a fixed sequence of families of hypotheses
- Rejoinder
- Rotation-based multiple testing in the multivariate linear model
- Classes of multiple decision functions strongly controlling FWER and FDR
- Sequentially rejective pairwise testing procedures
- Detecting multiple replicating signals using adaptive filtering procedures
- Exact testing with random permutations
- A rejection principle for sequential tests of multiple hypotheses controlling familywise error rates
- Multiple testing approaches for hypotheses in integrative genomics
- Error control in tree structured hypothesis testing
- Discussion on “Adaptive enrichment designs with a continuous biomarker” by Nigel Stallard
- Rejoinder to discussion on “Adaptive enrichment designs with a continuous biomarker”
- Signal localization: a new approach in signal discovery
- Only closed testing procedures are admissible for controlling false discovery proportions
- Simultaneous confidence intervals for ranks using the partitioning principle
- Analyzing environmental-trait interactions in ecological communities with fourth-corner latent variable models
- Tests for Jumps in Yield Spreads
- A sequential rejection testing method for high-dimensional regression with correlated variables
- Order selection with confidence for finite mixture models
- An improved closed procedure for testing multiple hypotheses
- The partitioning principle: a powerful tool in multiple decision theory
- On stepwise control of directional errors under independence and some dependence
- Minimally adaptive BH: a tiny but uniform improvement of the procedure of Benjamini and Hochberg
- Rejoinder
- Asymptotic optimality of the Westfall-Young permutation procedure for multiple testing under dependence
- Screening-assisted dynamic multiple testing with false discovery rate control
- A region-based multiple testing method for hypotheses ordered in space or time
- Applying the generalized partitioning principle to control the generalized familywise error rate
- Optimal exact tests for multiple binary endpoints
- The online closure principle
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