A matrix perturbation method for computing the steady-state probability distributions of probabilistic Boolean networks with gene perturbations

DOI10.1016/J.CAM.2010.10.021zbMATH Open1207.92015OpenAlexW2074817082MaRDI QIDQ629480FDOQ629480

Authors: Wei-Wei Xu, Wai-Ki Ching, Shuqin Zhang, Wen Li, Xiao Shan Chen 

Publication date: 9 March 2011

Published in: Journal of Computational and Applied Mathematics (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.cam.2010.10.021

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zbMATH Keywords

Boolean networksprobabilistic Boolean networkssteady-state probability distributiongene perturbationperturbation matrix

Mathematics Subject Classification ID

Systems biology, networks (92C42) Combinatorial probability (60C05)

Cites Work

• Title not available (Why is that?)
• Control of Boolean networks: hardness results and algorithms for tree structured networks
• Markov chains: models, algorithms and applications
• New perturbation analysis for generalized saddle point systems

Cited In (12)

• On the long-run sensitivity of probabilistic Boolean networks
• The effects of node exclusion on the centrality measures in graph models of interacting economic agents
• On computation of the steady-state probability distribution of probabilistic Boolean networks with gene perturbation
• Dimension reduction of large sparse AND-NOT network models
• Construction of probabilistic Boolean networks from a prescribed transition probability matrix: a maximum entropy rate approach.
• On generating optimal sparse probabilistic Boolean networks with maximum entropy from a positive stationary distribution.
• Steady-state probabilities for attractors in probabilistic Boolean networks
• Fitting Boolean networks from steady state perturbation data
• Steady-state analysis of probabilistic Boolean networks
• Function perturbation impact on stability in distribution of probabilistic Boolean networks
• GPU-accelerated steady-state computation of large probabilistic Boolean networks
• Relationships between probabilistic Boolean networks and dynamic Bayesian networks as models of gene regulatory networks

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