On temporal homogenization in the numerical simulation of atherosclerotic plaque growth
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Publication:6370544
arXiv2106.09394MaRDI QIDQ6370544FDOQ6370544
Thomas Richter, Stefan Frei, Alexander Heinlein
Publication date: 17 June 2021
Abstract: A temporal homogenization approach for the numerical simulation of atherosclerotic plaque growth is extended to fully coupled fluid-structure interaction (FSI) simulations. The numerical results indicate that the two-scale approach yields significantly different results compared to a simple heuristic averaging, where only stationary long-scale FSI problems are solved, confirming the importance of incorporating stress variations on small time-scales. In the homogenization approach, a periodic fine-scale problem, which is periodic with respect to the heart beat, has to be solved for each long-scale time step. Even if no exact initial conditions are available, periodicity can be achieved within only 2-3 heart beats by simple time-stepping.
Finite element, Rayleigh-Ritz and Galerkin methods for initial value and initial-boundary value problems involving PDEs (65M60) Fluid-solid interactions (including aero- and hydro-elasticity, porosity, etc.) (74F10) Finite element methods applied to problems in fluid mechanics (76M10) Physiological flows (76Z05) Physiological flow (92C35)
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