Dynamic stabilization in the PU1-GATA1 circuit using a model with time-dependent kinetic change

DOI10.1007/S11538-010-9615-3MaRDI QIDQ644487zbMATH OpenOpenAlexWikidataFDO

Authors Jay L. Michaels, Vincent Naudot, Larry S. Liebovitch

Publication date 4 November 2011

Published in Bulletin of Mathematical Biology (Search for Journal in Brave)

Copyright license Creative Commons Attribution-NonCommercial 4.0 International

Full work available at URL https://doi.org/10.1007/s11538-010-9615-3

zbMATH Keywords

blood stem cell fate commitmentcomputational biology of gene regulatory networks

Mathematics Subject Classification ID

Genetics and epigenetics (92D10) Probabilistic models, generic numerical methods in probability and statistics (65C20) Systems biology, networks (92C42) Feedback control (93B52) Adaptive control/observation systems (93C40)

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Cites work

• scientific article; zbMATH DE number 819507 (Why is no real title available?)
• A bistable genetic switch which does not require high co-operativity at the promoter: a two-timescale model for the PU.1-GATA-1 interaction
• A family of embedded Runge-Kutta formulae
• Stochasticity in single gene expression with both intrinsic noise and fluctuation in kinetic parameters

Cited in

(5)

• Limit-cycle oscillatory coexpression of cross-inhibitory transcription factors: a model mechanism for lineage promiscuity
• Towards an understanding of lineage specification in hematopoietic stem cells: a mathematical model for the interaction of transcription factors GATA-1 and PU.1
• ROBUST DEPENDENCIES AND STRUCTURES IN STEM CELL DIFFERENTIATION
• Mathematical modelling of stem cell differentiation: the PU.1-GATA-1 interaction
• A bistable genetic switch which does not require high co-operativity at the promoter: a two-timescale model for the PU.1-GATA-1 interaction

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