Design of regulation and dynamics in simple biochemical pathways

DOI10.1007/S00285-010-0375-3MaRDI QIDQ659024zbMATH OpenOpenAlexWikidataFDO

Authors Ram Rup Sarkar, R. Maithreye, Somdatta Sinha

Publication date 9 February 2012

Published in Journal of Mathematical Biology (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1007/s00285-010-0375-3

zbMATH Keywords

Global stabilityGene regulationNegative feedbackTime delaysTransient dynamics

Mathematics Subject Classification ID

Biochemistry, molecular biology (92C40) Stability theory of functional-differential equations (34K20) Qualitative investigation and simulation of models involving functional-differential equations (34K60) Cell biology (92C37)

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Cites work

• scientific article; zbMATH DE number 4077032 (Why is no real title available?)
• scientific article; zbMATH DE number 3702452 (Why is no real title available?)
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• A method for proving the non-existence of limit cycles
• Delay differential equations: with applications in population dynamics
• Gene expression time delays and Turing pattern formation systems
• Global stability in time-delayed single-species dynamics
• Instability and complex dynamic behaviour in population models with long time delays
• Introduction to functional differential equations
• Mathematical model of the cell division cycle of fission yeast
• Permanence and positive periodic solution for a single-species nonautonomous delay diffusive models
• Piecewise-linear models of genetic regulatory networks: equilibria and their stability
• The effect of negative feedback on noise propagation in transcriptional gene networks

Cited in

(6)

• Modelling simple biochemical networks
• Propagation of extrinsic perturbation in multistep biochemical pathways
• Long lived transients in gene regulation
• A theoretic control approach in signal-controlled metabolic pathways
• Design principles for robust biochemical reaction networks: what works, what cannot work, and what might almost work
• How quantitative measures unravel design principles in multi-stage phosphorylation cascades

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