Computational model of the cancer necrotic core formation in a tumor-on-a-chip device

DOI10.1016/J.JTBI.2024.111893MaRDI QIDQ6594270zbMATH OpenFDO

Authors Elton Diêgo Bonifácio, Cleudmar Amaral Araújo, Marcília Valéria Guimarães, Márcio Peres de Souza, Thiago Parente Lima, Bethânia Alves de Avelar Freitas, Libardo Andrés González-Torres

Publication date 28 August 2024

Published in Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/J.JTBI.2024.111893

zbMATH Keywords

finite element analysismicrofluidic devicesnecrotic coretumor cells

Mathematics Subject Classification ID

Computational methods for problems pertaining to biology (92-08) Pathology, pathophysiology (92C32) Cell biology (92C37)

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Cites work

• A mathematical model for the glucose-lactate metabolism of in vitro cancer cells
• scientific article; zbMATH DE number 1005391 (Why is no real title available?)
• Mathematical modelling of tumour acidity
• Modelling the formation of necrotic regions in avascular tumours
• Necrotic core in EMT6/Ro tumour spheroids: is it caused by an ATP deficit?

Cited in

(1)

• A 3D computational study on the formation and progression of tumor cells in diffuse gastric cancer

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