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Designing a longitudinal clinical trial based on a composite endpoint: sample size, monitoring, and adaptation

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Publication:6629323
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DOI10.1002/SIM.9416zbMATH Open1547.62445MaRDI QIDQ6629323FDOQ6629323


Authors: David A. Schoenfeld, Ritesh Ramchandani, Dianne M. Finkelstein Edit this on Wikidata


Publication date: 29 October 2024

Published in: Statistics in Medicine (Search for Journal in Brave)






zbMATH Keywords

survivalclinical trialwin ratiocomposite testFinkelstein-Schoenfeld test


Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10)


Cites Work

  • An alternative approach to confidence interval estimation for the win ratio statistic
  • Title not available (Why is that?)
  • A simple algorithm for designing group sequential clinical trials
  • On the win-ratio statistic in clinical trials with multiple types of event
  • On the inefficiency of the adaptive design for monitoring clinical trials
  • Adaptive design theory and implementation using SAS and R.
  • Graphing the win ratio and its components over time






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