Analysis of singularly perturbed stochastic chemical reaction networks motivated by applications to epigenetic cell memory

DOI10.1137/23M1592389MaRDI QIDQ6629685zbMATH OpenFDO

Authors Simone Bruno, Felipe A. Campos, Yi Fu, Domitilla Del Vecchio, R. J. Williams

Publication date 30 October 2024

Published in SIAM Journal on Applied Dynamical Systems (Search for Journal in Brave)

zbMATH Keywords

singular perturbationmean first passage timescontinuous time Markov chainepigenetic cell memorychromatin modification circuitsmultimodal stationary distribution

Mathematics Subject Classification ID

Applications of continuous-time Markov processes on discrete state spaces (60J28) Biochemistry, molecular biology (92C40) Systems biology, networks (92C42)

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Cites work

• scientific article; zbMATH DE number 51724 (Why is no real title available?)
• scientific article; zbMATH DE number 3272022 (Why is no real title available?)
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• Markov Chains
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• Perturbation analysis for denumerable Markov chains with application to queueing models
• Stochastic analysis of biochemical systems
• The Role of the Group Generalized Inverse in the Theory of Finite Markov Chains
• The first Laurent series coefficients for singularly perturbed stochastic matrices
• Tunneling and metastability of continuous time Markov chains
• Tunneling and metastability of continuous time Markov chains. II: The nonreversible case

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