Derivation, identification and validation of a computational model of a novel synthetic regulatory network in yeast

DOI10.1007/S00285-010-0350-ZMaRDI QIDQ663155zbMATHOpenAlexWikidataFDO

Authors Lucia Marucci, Stefania Santini, Mario Di Bernardo, D. di Bernardo

Publication date 14 February 2012

Published in Journal of Mathematical Biology (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1007/s00285-010-0350-z

zbMATH Keywords

Parameter identificationHill functionsSynthetic biology

Mathematics Subject Classification ID

Biochemistry, molecular biology (92C40) Dynamical systems in biology (37N25) Systems biology, networks (92C42) Computational methods for problems pertaining to biology (92-08)

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• Modeling the dynamic behavior of biochemical regulatory networks
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Cites work

• scientific article; zbMATH DE number 1573291 (Why is no real title available?)
• scientific article; zbMATH DE number 1254125 (Why is no real title available?)
• scientific article; zbMATH DE number 1278315 (Why is no real title available?)
• scientific article; zbMATH DE number 1131224 (Why is no real title available?)
• A 3(2) pair of Runge-Kutta formulas
• A survey of cross-validation procedures for model selection
• An introduction to systems biology. Design principles of biological circuits.
• Identification of parametric models from experimental data. Transl. from an upd. French version by the authors, with the help of John Norton
• Model validation: a connection between robust control and identification
• Solving DDEs in Matlab
• System modeling in cellular biology. From concepts to nuts and bolts.

Cited in

(5)

• An experimental approach to identify dynamical models of transcriptional regulation in living cells
• Comparative study of the transcriptional regulatory networks of \textit{E. coli} and yeast: structural characteristics leading to marginal dynamic stability
• Generating synthetic signaling networks for in silico modeling studies
• Complexity analysis and parameter estimation of dynamic metabolic systems
• A yeast cell cycle pulse generator model shows consistency with multiple oscillatory and checkpoint mutant datasets

Describes a project that uses

Uses Software

• dde23
• PottersWheel

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