Derivation, identification and validation of a computational model of a novel synthetic regulatory network in yeast

DOI10.1007/S00285-010-0350-ZzbMATH Open1232.92050OpenAlexW1975928912WikidataQ51689540 ScholiaQ51689540MaRDI QIDQ663155FDOQ663155

Authors: Lucia Marucci, Stefania Santini, Mario Di Bernardo, D. di Bernardo 

Publication date: 14 February 2012

Published in: Journal of Mathematical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1007/s00285-010-0350-z

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zbMATH Keywords

Parameter identificationHill functionsSynthetic biology

Mathematics Subject Classification ID

Biochemistry, molecular biology (92C40) Dynamical systems in biology (37N25) Systems biology, networks (92C42) Computational methods for problems pertaining to biology (92-08)

Cites Work

• A survey of cross-validation procedures for model selection
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• Solving DDEs in Matlab
• An introduction to systems biology. Design principles of biological circuits.
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• Identification of parametric models from experimental data. Transl. from an upd. French version by the authors, with the help of John Norton
• Title not available (Why is that?)
• A 3(2) pair of Runge-Kutta formulas
• Model validation: a connection between robust control and identification
• System modeling in cellular biology. From concepts to nuts and bolts.
• Title not available (Why is that?)

Cited In (5)

• Comparative study of the transcriptional regulatory networks of \textit{E. coli} and yeast: structural characteristics leading to marginal dynamic stability
• A yeast cell cycle pulse generator model shows consistency with multiple oscillatory and checkpoint mutant datasets
• Generating synthetic signaling networks for in silico modeling studies
• An experimental approach to identify dynamical models of transcriptional regulation in living cells
• Complexity analysis and parameter estimation of dynamic metabolic systems

Uses Software

• dde23
• PottersWheel

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