Dual-agent dose-finding in phase I clinical trial -- an extension of rapid enrollment design

DOI10.1002/SIM.10185MaRDI QIDQ6652600zbMATH OpenFDO

Authors Yunfei Wang

Publication date 12 December 2024

Published in Statistics in Medicine (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1002/SIM.10185

zbMATH Keywords

Bayesian optimal interval designdose-findingpartial order continual reassessment methodrapid enrollment dual-agent design (REDD)

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10)

Cites work

• A Parallel Phase I/II Clinical Trial Design for Combination Therapies
• Bayesian optimal interval designs for phase I clinical trials
• Continual reassessment method for partial ordering
• Continual Reassessment Method: A Practical Design for Phase 1 Clinical Trials in Cancer
• Design and Analysis of Phase I Clinical Trials
• Designs for Single- or Multiple-Agent Phase I Trials
• Dose Finding for Continuous and Ordinal Outcomes with a Monotone Objective Function: A Unified Approach
• Evaluation of early phase dose finding algorithms in heterogeneous populations
• scientific article; zbMATH DE number 3390139 (Why is no real title available?)
• Statistical properties of the traditional algorithm-based designs for phase I cancer clinical trials
• Two‐Dimensional Dose Finding in Discrete Dose Space

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