Representation of multiple cellular phenotypes within tissue-level simulations of cardiac electrophysiology

DOI10.1007/S11538-018-0516-1MaRDI QIDQ670609zbMATH OpenOpenAlexWikidataFDO

Authors Louise A. Bowler, David J. Gavaghan, G. R. Mirams, Jonathan P. Whiteley

Publication date 18 March 2019

Published in Bulletin of Mathematical Biology (Search for Journal in Brave)

Copyright license Creative Commons Attribution 4.0 International

Full work available at URL https://europepmc.org/articles/pmc6320359

zbMATH Keywords

homogenisationcardiac electrophysiologybidomainmonodomainstem cell-derived cardiomyocytes

Mathematics Subject Classification ID

Physiology (general) (92C30) Cell biology (92C37)

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Cites work

• Derivation of the bidomain equations for a beating heart with a general microstructure
• Empirical study of an adaptive multiscale model for simulating cardiac conduction
• Mathematical physiology. I: Cellular physiology
• Mathematical physiology. II: Systems physiology
• Modelling the effect of gap junctions on tissue-level cardiac electrophysiology
• Synchronization of Pulse-Coupled Biological Oscillators

Cited in

(4)

• Modeling and simulation of human induced pluripotent stem cell‐derived cardiac tissue
• Application of stochastic phenomenological modelling to cell-to-cell and beat-to-beat electrophysiological variability in cardiac tissue
• Virtual cell and tissue dynamics of ectopic activation of the ventricles
• Modelling and simulation for preclinical cardiac safety assessment of drugs with human iPSC-derived cardiomyocytes

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