A two-stage design for comparative clinical trials: the heteroscedastic solution

DOI10.1007/S13571-017-0147-9MaRDI QIDQ721618zbMATH OpenOpenAlexFDO

Authors Elena M. Buzaianu, Pinyuen Chen

Publication date 19 July 2018

Published in Sankhyā. Series B (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1007/s13571-017-0147-9

zbMATH Keywords

clinical trialsranking and selectionhybrid selection and testing designStein-type two stage design

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Statistical ranking and selection procedures (62F07) Sequential statistical design (62L05)

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Cites work

• scientific article; zbMATH DE number 3913510 (Why is no real title available?)
• scientific article; zbMATH DE number 3527652 (Why is no real title available?)
• scientific article; zbMATH DE number 3624609 (Why is no real title available?)
• scientific article; zbMATH DE number 3089535 (Why is no real title available?)
• A Stein-Type Two-Sample Procedure for Comparing Normal Means
• A Two-Sample Test for a Linear Hypothesis Whose Power is Independent of the Variance
• A Two-Stage Design for Choosing among Several Experimental Treatments and a Control in Clinical Trials
• Bayesian adaptive methods for clinical trials
• On the Non-Existence of Tests of "Student's" Hypothesis Having Power Functions Independent of $\sigma$
• Some Fixed-Sample Ranking and Selection Problems
• The statistical sleuth. A course in methods of data analysis
• Two-stage selection and testing designs for comparative clinical trials

Cited in

(7)

• A selection and testing procedure for comparing several experimental treatments with a control
• A multiple three-decision procedures for comparing several treatments with a control under heteroscedasticity
• Two-sample two-stage and purely sequential methodologies for tests of hypotheses with applications: comparing normal means when the two variances are unknown and unequal
• A Two-Stage Design for Choosing among Several Experimental Treatments and a Control in Clinical Trials
• Two-stage selection and testing designs for comparative clinical trials
• Two-Stage Designs with Additional Futility Tests for Phase II Clinical Trials with Heterogeneous Patient Populations
• A hybrid geometric phase II/III clinical trial design based on treatment failure time and toxicity

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Uses Software

• Sleuth3

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