Mechanistic modeling explains the dsRNA length-dependent activation of the RIG-I mediated immune response

DOI10.1016/J.JTBI.2020.110336zbMath1455.92052OpenAlexW3026693787WikidataQ95645873 ScholiaQ95645873MaRDI QIDQ827851

Pia Bachmann, Lars Kaderali, Darius Schweinoch, Diana Clausznitzer, Marco Binder

Publication date: 13 January 2021

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jtbi.2020.110336

zbMATH Keywords

mathematical modelODEantiviral responsebinding mechanismpattern recognition receptor (PRR)

Mathematics Subject Classification ID

Biochemistry, molecular biology (92C40)

Uses Software

• Data2Dynamics

Cites Work

• Mathematical models for immunology: current state of the art and future research directions
• Identifiability and observability analysis for experimental design in nonlinear dynamical models

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