Mathematical models for immunology: current state of the art and future research directions
From MaRDI portal
Publication:518216
DOI10.1007/s11538-016-0214-9zbMath1361.92033OpenAlexW2527772066WikidataQ38809377 ScholiaQ38809377MaRDI QIDQ518216
Raluca Eftimie, Joseph J. Gillard, Doreen A. Cantrell
Publication date: 28 March 2017
Published in: Bulletin of Mathematical Biology (Search for Journal in Brave)
Full work available at URL: https://doi.org/10.1007/s11538-016-0214-9
Medical applications (general) (92C50) Research exposition (monographs, survey articles) pertaining to biology (92-02)
Related Items
Mechanistic modeling explains the dsRNA length-dependent activation of the RIG-I mediated immune response ⋮ Qualitative analysis of kinetic-based models for tumor-immune system interaction ⋮ Mathematical model of the aseptic inflammation dynamics ⋮ Toward a model-free feedback control synthesis for treating acute inflammation ⋮ Mathematical modeling of tumor-induced immunosuppression by myeloid-derived suppressor cells: implications for therapeutic targeting strategies ⋮ Dendritic immunotherapy improvement for an optimal control murine model ⋮ Mathematical modeling approach of cancer immunoediting reveals new insights in targeted-therapy and timing plan of cancer treatment ⋮ Modelling and investigation of the \(\mathrm{CD}4^+\) T cells -- macrophages paradox in melanoma immunotherapies ⋮ Modeling LSD1-mediated tumor stagnation ⋮ Mathematical modelling for the role of CD\(4^+\)T cells in tumor-immune interactions ⋮ Pattern formation in a nonlocal mathematical model for the multiple roles of the TGF-\(\beta\) pathway in tumour dynamics ⋮ A nonlinear mathematical model of cell-mediated immune response for tumor phenotypic heterogeneity ⋮ MATHEMATICAL INSIGHTS INTO THE DYNAMICS OF INNATE IMMUNE RESPONSE DURING INFLAMMATION ⋮ Probabilistically certified region of attraction of a tumor growth model with combined chemo‐ and immunotherapy ⋮ Stability Analysis of the Immune System Induced by Chemotaxis ⋮ Modeling the development of cellular exhaustion and tumor-immune stalemate ⋮ Analysis of tumor-immune functional responses in a mathematical model of neoantigen cancer vaccines ⋮ Global boundedness of the immune chemotaxis system with general kinetic functions ⋮ A mixture-like model for tumor-immune system interactions ⋮ Characterizing chemotherapy-induced neutropenia and monocytopenia through mathematical modelling ⋮ Time-adaptive determination of drug efficacy in mathematical model of HIV infection ⋮ Treatment of melanoma with dendritic cell vaccines and immune checkpoint inhibitors: a mathematical modeling study ⋮ Modeling the effect of memory in the adaptive immune response ⋮ Modelling Stochastic and Deterministic Behaviours in Virus Infection Dynamics ⋮ Nonlinear effects in the dynamics of HIV-1 infection predicted by mathematical model with multiple delays ⋮ Interplay between reaction and diffusion processes in governing the dynamics of virus infections ⋮ CAR T cell therapy in B-cell acute lymphoblastic leukaemia: insights from mathematical models ⋮ Cheater-altruist synergy in public goods games ⋮ Modeling of fusion inhibitor treatment of RSV in African green monkeys ⋮ A structural methodology for modeling immune-tumor interactions including pro- and anti-tumor factors for clinical applications ⋮ Stability and Hopf bifurcations in a competitive tumour-immune system with intrinsic recruitment delay and chemotherapy ⋮ Controlling IL-7 injections in HIV-infected patients ⋮ Robust domain of attraction estimation for a tumor growth model ⋮ An investigation on Monod-Haldane immune response based tumor-effector-interleukin-2 interactions with treatments ⋮ A size and space structured model describing interactions of tumor cells with immune cells reveals cancer persistent equilibrium states in tumorigenesis ⋮ Stochastic Analog of the Dynamic Model of HIV-1 Infection Described by Delay Differential Equations ⋮ Algorithmic asymptotic analysis: extending the arsenal of cancer immunology modeling ⋮ A mathematical model for the immune-mediated theory of metastasis ⋮ Immigration-induced phase transition in a regulated multispecies birth-death process ⋮ Response of patients with melanoma to immune checkpoint blockade -- insights gleaned from analysis of a new mathematical mechanistic model ⋮ Global boundedness and stability analysis of the quasilinear immune chemotaxis system ⋮ Dynamics and analysis of a mathematical model of neuroblastoma treated with Celyvir
Uses Software
Cites Work
- Unnamed Item
- Unnamed Item
- Multi-armed bandit models for the optimal design of clinical trials: benefits and challenges
- Optimal control in a model of dendritic cell transfection cancer immunotherapy
- Stochastic approximation to the T cell mediated specific response of the immune system
- A systematic survey of the response of a model NF-\(\kappa\)B signalling pathway to \(\mathrm{TNF}\alpha\) stimulation
- How many TCR clonotypes does a body maintain?
- Optimal control strategy for abnormal innate immune response
- A hybrid model of tumor-stromal interactions in breast cancer
- Mathematical models of memory \(\mathrm{CD}8^+\) T-cell repertoire dynamics in response to viral infections
- The resolution of inflammation: a mathematical model of neutrophil and macrophage interactions
- A quantitative model of thermal injury-induced acute inflammation
- Mathematical modelling of immune response in tissues
- On the modelling of genetic mutations and immune system competition
- Optimal response to chemotherapy for a mathematical model of tumor-immune dynamics
- Quantifying T lymphocyte turnover
- Hybrid models of cell and tissue dynamics in tumor growth
- Treatment strategies for combining immunostimulatory oncolytic virus therapeutics with dendritic cell injections
- Rival approaches to mathematical modelling in immunology
- New developments in the application of optimal control theory to therapeutic protocols
- Mutation and control of the human immunodeficiency virus
- Mechanistic simulations of inflammation: current state and future prospects
- A simple mathematical model of signaling resulting from the binding of lipopolysaccharide with toll-like receptor 4 demonstrates inherent preconditioning behavior
- A model of TLR4 signaling and tolerance using a qualitative, particle-event-based method: Introduction of spatially configured stochastic reaction chambers (SCSRC)
- Stability and bifurcations for the chronic state in Marchuk's model of an immune system
- Modeling the role of IL-2 in the interplay between CD4+ helper and regulatory T cells: assessing general dynamical properties
- Optimal number of regulatory T cells
- Modeling anti-tumor Th1 and Th2 immunity in the rejection of melanoma
- Wound healing angiogenesis: the clinical implications of a simple mathematical model
- Stochastic effects and bistability in T cell receptor signaling
- Stochastic niche structure and diversity maintenance in the T cell repertoire
- A model for coupling within-host and between-host dynamics in an infectious disease
- Computational modeling of microabscess formation
- A mathematical model for coupling within-host and between-host dynamics in an environmentally-driven infectious disease
- A cellular automata model of tumor-immune system interactions
- Modeling regulation mechanisms in the immune system
- A dynamical model of human immune response to influenza A virus infection
- Cancer immunotherapy, mathematical modeling and optimal control
- Mathematical modeling of allergy and specific immunotherapy: Th1-Th2-Treg interactions
- A mathematical model of the immune and neuroendocrine systems mutual regulation under the technogenic chemical factors impact
- Bifurcation analysis in models of tumor and immune system interactions
- Mathematical model of a three-stage innate immune response to a pneumococcal lung infection
- Modeling the host response to inhalation anthrax
- Mathematical model of macrophage-facilitated breast cancer cells invasion
- Macrophage-based anti-cancer therapy: Modelling different modes of tumour targeting
- Interactions between the immune system and cancer: A brief review of non-spatial mathematical models
- Chemotherapy for tumors: An analysis of the dynamics and a study of quadratic and linear optimal controls
- Immunology and immunity against infection: general rules
- Asymptotic analysis of a nonlinear integro-differential system modeling the immune response
- Predicting pathogen-specific CD8 T cell immune responses from a modeling approach
- Memory versus effector immune responses in oncolytic virotherapies
- The role of tunable activation thresholds in the dynamics of autoimmunity
- A mathematical model of intrahost pneumococcal pneumonia infection dynamics in murine strains
- On a Mathematical Model of Adaptive Immune Response to Viral Infection
- Optimal Control in Coupled Within-host and Between-host Models
- Robust H∞ observer-based tracking control of stochastic immune systems under environmental disturbances and measurement noises
- MATHEMATICAL MODELING FOR KELOID FORMATION TRIGGERED BY VIRUS: MALIGNANT EFFECTS AND IMMUNE SYSTEM COMPETITION
- Mathematical Immunology of Infectious Diseases
- On Identifiability of Nonlinear ODE Models and Applications in Viral Dynamics
- Mathematical modelling the age dependence of Epstein-Barr virus associated infectious mononucleosis
- Rule-Based Modelling of Cellular Signalling
- Sensitivity analysis of partial differential equations: A case for functional sensitivity
- FROM THE MODELING OF THE IMMUNE HALLMARKS OF CANCER TO A BLACK SWAN IN BIOLOGY
- Hopf bifurcation in a gene regulatory network model: Molecular movement causes oscillations
