A mathematical model for the immune-mediated theory of metastasis

DOI10.1101/565531MaRDI QIDQ2328275zbMATH OpenOpenAlexWikidataFDO

Authors Adam Rhodes, Thomas Hillen

Publication date 10 October 2019

Published in Journal of Theoretical Biology (Search for Journal in Brave)

Copyright license Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International

Full work available at URL https://doi.org/10.1016/j.jtbi.2019.109999

zbMATH Keywords

immune responseimmunotherapiesmetastasismetastatic cascade

Mathematics Subject Classification ID

Physiology (general) (92C30) Medical applications (general) (92C50)

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Cites work

• A mathematical framework for modelling the metastatic spread of cancer
• A reaction-diffusion model for radiation-induced bystander effects
• A stochastic model for the sizes of detectable metastases
• Interactions between the immune system and cancer: A brief review of non-spatial mathematical models
• Mathematical analysis of a two-dimensional population model of metastatic growth including angiogenesis
• Mathematical modeling of the role of \textit{survivin} on dedifferentiation and radioresistance in cancer
• Mathematical models for immunology: current state of the art and future research directions
• Modeling the dichotomy of the immune response to cancer: cytotoxic effects and tumor-promoting inflammation
• Modeling tumor regrowth and immunotherapy
• Nonlinear dynamics of immunogenic tumors: Parameter estimation and global bifurcation analysis
• Stochastic dynamics of metastasis formation
• Suppression of metastasis by primary tumor and acceleration of metastasis following primary tumor resection: A natural law?
• The evolution of tumor metastases during clonal expansion
• The re-polarisation of M2 and M1 macrophages and its role on cancer outcomes

Cited in

(7)

• Implications of immune-mediated metastatic growth on metastatic dormancy, blow-up, early detection, and treatment
• Antigen receptor therapy in bone metastasis via optimal control for different human life stages
• Cancer cell eradication in a 6D metastatic tumor model with time delay
• THE METASTASIS BEHAVIOR IN THE CERVICAL CANCER MATHEMATICAL MODEL
• A role of effector \(\text{CD}8^+\) T cells against circulating tumor cells cloaked with platelets: insights from a mathematical model
• Modelling of cancer stem cell driven solid tumors
• Mathematical model of tumor-macrophage interactions: elucidating the tumor-driven macrophage phenotype reprogramming

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