How many TCR clonotypes does a body maintain?

DOI10.1016/J.JTBI.2015.10.016MaRDI QIDQ304769zbMATH OpenOpenAlexWikidataFDO

Authors Grant Lythe, Robin E. Callard, Rollo L. Hoare, Carmen Molina-París

Publication date 26 August 2016

Published in Journal of Theoretical Biology (Search for Journal in Brave)

Copyright license Creative Commons Attribution 4.0 International

Full work available at URL https://doi.org/10.1016/j.jtbi.2015.10.016

zbMATH Keywords

competitionextinctionhomeostasisT cellsstochastic modellingclonal repertoire

Mathematics Subject Classification ID

Physiology (general) (92C30) Cell biology (92C37)

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Cites work

• scientific article; zbMATH DE number 48952 (Why is no real title available?)
• scientific article; zbMATH DE number 1194938 (Why is no real title available?)
• scientific article; zbMATH DE number 1237738 (Why is no real title available?)
• Development of the T-cell repertoire: Clone size distribution
• Handbook of stochastic methods for physics, chemistry and natural sciences.
• Methods for diversity and overlap analysis in T-cell receptor populations
• Quantifying T lymphocyte turnover
• Stochastic modelling for systems biology.
• Stochastic niche structure and diversity maintenance in the T cell repertoire
• Stochastic population processes. Analysis, approximation, simulations.
• The limiting conditional probability distribution in a stochastic model of T cell repertoire maintenance

Cited in

(12)

• Stochastic competitive exclusion in the maintenance of the naïve T cell repertoire
• Dynamics of T cell receptor distributions following acute thymic atrophy and resumption
• A mathematical model of the effects of aging on naive T cell populations and diversity
• The role of the T-helper/T-suppressor ratio in the adaptive immune response: a dynamical model
• The T cells in an ageing virtual mouse
• Mathematical models for immunology: current state of the art and future research directions
• Mathematical characterization of private and public Immune receptor sequences
• Quantitative immunology for physicists
• Exact steady-state distributions of multispecies birth-death-immigration processes: effects of mutations and carrying capacity on diversity
• Decline in excision circles requires homeostatic renewal or homeostatic death of naive T cells
• Stochastic descriptors to study the fate and potential of naive T cell clonotypes in the periphery
• Immigration-induced phase transition in a regulated multispecies birth-death process

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