Investigation of the age-at-onset heterogeneity in type 1 diabetes through mathematical mod\-el\-ing

DOI10.1016/J.MBS.2006.03.021MaRDI QIDQ850112zbMATH OpenOpenAlexWikidataFDO

Authors Xujing Wang, Zening He, Soumitra Ghosh

Publication date 15 November 2006

Published in Mathematical Biosciences (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/j.mbs.2006.03.021

zbMATH Keywords

stability analysisdiabetestypeperturbation expansion\(\beta\) -cell turnoverage-at-onset heterogeneitydynamics of disease

Mathematics Subject Classification ID

Medical applications (general) (92C50) Dynamical systems in biology (37N25) Stability theory for ordinary differential equations (34D99)

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Cites work

• scientific article; zbMATH DE number 798177 (Why is no real title available?)
• Quantifying macrophage defects in type 1 diabetes

Cited in

(2)

• Modelling the onset of Type 1 diabetes: can impaired macrophage phagocytosis make the difference between health and disease?
• Modeling dynamic changes in type 1 diabetes progression: quantifying \(\beta\)-cell variation after the appearance of islet-specific autoimmune responses

Describes a project that uses

Uses Software

• MINMOD

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