Completeness and unbiased estimation of mean vector in the multivariate group sequential case

DOI10.1016/J.JMVA.2006.01.001MaRDI QIDQ873618zbMATH OpenOpenAlexFDO

Authors Aiyi Liu, Chengqing Wu, Weishi Yuan, Kai F. Yu

Publication date 29 March 2007

Published in Journal of Multivariate Analysis (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/j.jmva.2006.01.001

zbMATH Keywords

biasmean squared errorinterim analysisminimum variancemultiple endpointsmedical trialsrestricted completenesstruncation-adaptation

Mathematics Subject Classification ID

Estimation in multivariate analysis (62H12) Sequential statistical design (62L05) Sequential statistical analysis (62L10) Sufficient statistics and fields (62B05)

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Cites work

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• A Computationally Simpler Algorithm for the UMVUE of a Normal Mean Following a Group Sequential Trial
• An approximate likelihood ratio test for a normal mean vector with nonnegative components with application to clinical trials
• Closed Testing Procedures for Group Sequential Clinical Trials with Multiple Endpoints
• Completeness in the Sequential Case
• Conditional Expectation and Unbiased Sequential Estimation
• Discrete Sequential Boundaries for Clinical Trials
• Group Sequential Distribution-Free Methods for the Analysis of Multivariate Observations
• Group Sequential Tests for Bivariate Response: Interim Analyses of Clinical Trials with Both Efficacy and Safety Endpoints
• Nonparametric sequential testing in clinical trials with incomplete multivariate observations
• On The Design and Analysis of Randomized Clinical Trials with Multiple Endpoints
• Sequential analysis. Tests and confidence intervals
• The distribution of brownian motion on linear stopping boundaries
• Unbiased estimation following a group sequential test
• What is the Laplace Transform?

Cited in

(2)

• Estimation following a group sequential test for distributions in the one-parameter exponential family
• Point estimation for adaptive trial designs. I: A methodological review

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