Differentiated cell behavior: a multiscale approach using measure theory
From MaRDI portal
Publication:887397
DOI10.1007/S00285-014-0846-ZzbMATH Open1331.35350OpenAlexW2076269675WikidataQ51018189 ScholiaQ51018189MaRDI QIDQ887397FDOQ887397
Authors: Annachiara Colombi, M. Scianna, Andrea Tosin 
Publication date: 26 October 2015
Published in: Journal of Mathematical Biology (Search for Journal in Brave)
Abstract: This paper deals with the derivation of a collective model of cell populations out of an individual-based description of the underlying physical particle system. By looking at the spatial distribution of cells in terms of time-evolving measures, rather than at individual cell paths, we obtain an ensemble representation stemming from the phenomenological behavior of the single component cells. In particular, as a key advantage of our approach, the scale of representation of the system, i.e., microscopic/discrete vs. macroscopic/continuous, can be chosen a posteriori according only to the spatial structure given to the aforesaid measures. The paper focuses in particular on the use of different scales based on the specific functions performed by cells. A two-population hybrid system is considered, where cells with a specialized/differentiated phenotype are treated as a discrete population of point masses while unspecialized/undifferentiated cell aggregates are represented with a continuous approximation. Numerical simulations and analytical investigations emphasize the role of some biologically relevant parameters in determining the specific evolution of such a hybrid cell system.
Full work available at URL: https://arxiv.org/abs/1108.1212
Recommendations
- A measure-theoretic model for collective cell migration and aggregation
- Multi-scale modelling in cell dynamics
- Complexity and mathematical tools toward the modelling of multicellular growing systems
- Coherent modelling switch between pointwise and distributed representations of cell aggregates
- Multiscale biological tissue models and flux-limited chemotaxis for multicellular growing systems
PDEs in connection with biology, chemistry and other natural sciences (35Q92) Cell movement (chemotaxis, etc.) (92C17)
Cites Work
- Title not available (Why is that?)
- A HYBRID MODEL FOR TUMOR SPHEROID GROWTH IN VITRO I: THEORETICAL DEVELOPMENT AND EARLY RESULTS
- A cellular Potts model simulating cell migration on and in matrix environments
- A hybrid mathematical model for self-organizing cell migration in the zebrafish lateral line
- A hybrid model of tumor-stromal interactions in breast cancer
- A measure-theoretic model for collective cell migration and aggregation
- An interacting particle system modelling aggregation behavior: from individuals to populations
- Asymptotic Behavior of a System of Stochastic Particles Subject to Nonlocal Interactions
- COARSE GRAINING IN SIMULATED CELL POPULATIONS
- Cellular Potts models. Multiscale extensions and biological applications
- Cellular automaton modeling of biological pattern formation. Characterization, applications, and analysis. With a foreword by Philip K. Maini
- Continuous and discrete mathematical models of tumor-induced angiogenesis
- Existence and approximation of probability measure solutions to models of collective behaviors
- Generalized Wasserstein distance and its application to transport equations with source
- Global nonexistence for a semilinear Petrovsky equation
- Gradient flows in metric spaces and in the space of probability measures
- Measure solutions for non-local interaction PDEs with two species
- Multi-scale models of cell and tissue dynamics
- Multiscale developments of the cellular Potts model
- Multiscale modeling of granular flows with application to crowd dynamics
- Multiscale modeling of pedestrian dynamics
- Particle, kinetic, and hydrodynamic models of swarming
- Pedestrian flows in bounded domains with obstacles
- Single-cell-based models in biology and medicine.
- Stochastic modelling of tumour-induced angiogenesis
- The Derivation of Chemotaxis Equations as Limit Dynamics of Moderately Interacting Stochastic Many-Particle Systems
- Three-dimensional multispecies nonlinear tumor growth. II: Tumor invasion and angiogenesis
- Time-evolving measures and macroscopic modeling of pedestrian flow
- Transport equation with nonlocal velocity in Wasserstein spaces: convergence of numerical schemes
Cited In (23)
- Stability of a non-local kinetic model for cell migration with density dependent orientation bias
- Modelling chase-and-run migration in heterogeneous populations
- Multi-cue kinetic model with non-local sensing for cell migration on a fiber network with chemotaxis
- Modelling physical limits of migration by a kinetic model with non-local sensing
- A hybrid model of collective motion of discrete particles under alignment and continuum chemotaxis
- A hybrid mathematical model for self-organizing cell migration in the zebrafish lateral line
- Well-posedness of a system of transport and diffusion equations in space of measures
- Kinetic models with non-local sensing determining cell polarization and speed according to independent cues
- Extension of tumor fingers: a comparison between an individual-cell based model and a measure theoretic approach
- Thermostatted kinetic theory in measure spaces: well-posedness
- Quantifying Cellular Pluripotency and Pathway Robustness Through Forman-Ricci Curvature
- A particle model analysing the behavioural rules underlying the collective flight of a bee swarm towards the new nest
- Derivation of continuum models from discrete models of mechanical forces in cell populations
- A Genuinely Hybrid, Multiscale 3D Cancer Invasion and Metastasis Modelling Framework
- A measure-theoretic model for collective cell migration and aggregation
- Modelling collective cell migration: neural crest as a model paradigm
- Adhesion and volume constraints via nonlocal interactions determine cell organisation and migration profiles
- A hybrid multiscale model for cancer invasion of the extracellular matrix
- The Mean-Field Limit for Hybrid Models of Collective Motions with Chemotaxis
- Coherent modelling switch between pointwise and distributed representations of cell aggregates
- Scaling laws of cell-fate responses to transient stress
- A coherent modeling procedure to describe cell activation in biological systems
- From individual behaviour to an evaluation of the collective evolution of crowds along footbridges
This page was built for publication: Differentiated cell behavior: a multiscale approach using measure theory
Report a bug (only for logged in users!)Click here to report a bug for this page (MaRDI item Q887397)
