Incorporating prior parameter uncertainty in the design of sampling schedules for pharmacokinetic parameter estimation experiments

DOI10.1016/0025-5564(90)90141-KMaRDI QIDQ913435zbMATH OpenOpenAlexWikidataFDO

Authors David Z. D'Argenio

Publication date 1990

Published in Mathematical Biosciences (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/0025-5564(90)90141-k

zbMATH Keywords

nonlinear parameter estimationAPI-optimal designsexpected posterior informationpharmacokinetic sample schedule design problemplasma concentration of a drugprior parameter uncertainty

Mathematics Subject Classification ID

Statistical aspects of information-theoretic topics (62B10) Applications of statistics to biology and medical sciences; meta analysis (62P10) Optimal statistical designs (62K05)

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Cites work

• scientific article; zbMATH DE number 3180539 (Why is no real title available?)
• scientific article; zbMATH DE number 3538668 (Why is no real title available?)
• A Mathematical Theory of Communication
• A maximum likelihood estimation method for random coefficient regression models
• DESIGN OF EXPERIMENTS IN NON-LINEAR SITUATIONS
• Discrete approximation of multivariate densities with application to Bayesian estimation
• Minimal sampling schedules for identification of dynamic models of metabolic systems of clinical interest: Case studies for two liver function tests
• On a Measure of the Information Provided by an Experiment
• Optimal nonuniform sampling interval and test-input design for identification of physiological systems from very limited data
• Robust experiment design via maximin optimization
• Robust experiment design via stochastic approximation

Cited in

(6)

• Optimizing designs in clinical trials with an application in treatment of epidermolysis bullosa simplex, a rare genetic skin disease
• Design optimality for models defined by a system of ordinary differential equations
• Stochastic optimization algorithms of a Bayesian design criterion for Bayesian parameter estimation of nonlinear regression models: Application in pharmacokinetics
• A Review of Modern Computational Algorithms for Bayesian Optimal Design
• Towards Bayesian experimental design for nonlinear models that require a large number of sampling times
• Information matrices with random regressors. Application to experimental design

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