Reoxygenation and split-dose response to radiation in a tumour model with Krogh-type vascular geometry

DOI10.1007/S11538-007-9287-9MaRDI QIDQ942907zbMATH OpenOpenAlexWikidataFDO

Authors Alberto Gandolfi, Alessandro Bertuzzi, Antonio Fasano, Carmela Sinisgalli

Publication date 8 September 2008

Published in Bulletin of Mathematical Biology (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1007/s11538-007-9287-9

zbMATH Keywords

radiotherapyreoxygenationdose splittingKrogh modeltumour cords

Mathematics Subject Classification ID

Medical applications (general) (92C50) PDEs in connection with biology, chemistry and other natural sciences (35Q92) Free boundary problems for PDEs (35R35)

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Cites work

• A Free Boundary Problem with Unilateral Constraints Describing the Evolution of a Tumor Cord Under the Influence of Cell Killing Agents
• Influence of time-dependent stochastic heterogeneity on the radiation response of a cell population
• Modelling solid tumour growth using the theory of mixtures
• Regression and regrowth of tumour cords following single-dose anticancer treatment

Cited in

(10)

• Optimal solution for a cancer radiotherapy problem
• A review of mathematical models for the formation of vascular networks
• Regression and regrowth of tumour cords following single-dose anticancer treatment
• Optimal weekly scheduling in fractionated radiotherapy: effect of an upper bound on the dose fraction size
• Response of tumor spheroids to radiation: Modeling and parameter estimation
• Repopulation of Tumour Cells during Radiotherapy Is Doubled during Treatment Gaps
• A mechanistic compartmental model for total antibody uptake in tumors
• Cell resensitization after delivery of a cycle-specific anticancer drug and effect of dose splitting: learning from tumour cords
• Selecting radiotherapy dose distributions by means of constrained optimization problems
• Phenotypic variation modulates the growth dynamics and response to radiotherapy of solid tumours under normoxia and hypoxia

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