Optimal cross-over designs for nonlinear mixed models using a first-order expansion

DOI10.1016/j.jspi.2008.02.012zbMath1149.62323OpenAlexW1972235239MaRDI QIDQ958774

Byron Jones, Jixian Wang

Publication date: 8 December 2008

Published in: Journal of Statistical Planning and Inference (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jspi.2008.02.012

zbMATH Keywords

optimal designcross-over designfirst-order expansionmultivariate linear mixed modelsnonlinear mixed effect models

Mathematics Subject Classification ID

Estimation in multivariate analysis (62H12) Optimal statistical designs (62K05)

Cites Work

• Optimal design and refinement of the linear model with applications to repeated measurements designs
• Design of cross-over trials for pharmacokinetic studies
• Optimal design in random-effects regression models
• Further Developments of the Fisher Information Matrix in Nonlinear Mixed Effects Models with Evaluation in Population Pharmacokinetics
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