Further Developments of the Fisher Information Matrix in Nonlinear Mixed Effects Models with Evaluation in Population Pharmacokinetics
DOI10.1081/BIP-120019267zbMATH Open1180.62182WikidataQ52017271 ScholiaQ52017271MaRDI QIDQ4803377FDOQ4803377
Authors: Sylvie Retout, France Mentré 
Publication date: 2 April 2003
Published in: Journal of Biopharmaceutical Statistics (Search for Journal in Brave)
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Statistical aspects of information-theoretic topics (62B10) Applications of statistics to biology and medical sciences; meta analysis (62P10) Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45)
Cites Work
- Laplace's approximation for nonlinear mixed models
- Optimal design in random-effects regression models
- Robust experiment design via stochastic approximation
- Design of cross-over trials for pharmacokinetic studies
- MULTIPLE-OBJECTIVE DESIGNS IN A DOSE-RESPONSE EXPERIMENT
- A simulated pseudo-maximum likelihood estimator for nonlinear mixed models.
- Population Pharmacokinetic/Pharmacodynamic Methodology and Applications: A Bibliography
Cited In (17)
- Optimal cross-over designs for nonlinear mixed models using a first-order expansion
- Design optimality for models defined by a system of ordinary differential equations
- An efficient algorithm for computation of information matrix in phase-type fitting
- On the choice of a prior for Bayesian D-optimal designs for the logistic regression model with a single predictor
- A new method for evaluation of the Fisher information matrix for discrete mixed effect models using Monte Carlo sampling and adaptive Gaussian quadrature
- Evaluation of the Fisher information matrix in nonlinear mixed effect models using adaptive Gaussian quadrature
- Fisher information for generalised linear mixed models
- Efficient algorithms for optimal designs with correlated observations in pharmacokinetics and dose-finding studies
- Approximate testing in two-stage nonlinear mixed models
- Simulation-based fully Bayesian experimental design for mixed effects models
- Optimal designs for random effect models with correlated errors with applications in population pharmacokinetics
- Optimal design for population PK/PD models
- Design optimization in nonlinear mixed effects models using cost functions: application to a joint model of infliximab and methotrexate pharmacokinetics
- A geometric characterization of \(c\)-optimal designs for heteroscedastic regression
- PkStaMp library for constructing optimal population designs for PK/PD studies
- Approximate Small-Sample Tests of Fixed Effects in Nonlinear Mixed Models
- Optimum Designs for Non-Linear Mixed Effects Models in the Presence of Covariates
Uses Software
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