Asymptotic behavior of the Poisson-Dirichlet distribution for large mutation rate

DOI10.1214/105051605000000818MaRDI QIDQ997941zbMATH OpenOpenAlexFDO

Authors Donald A. Dawson, Shui Feng

Publication date 8 August 2007

Published in The Annals of Applied Probability (Search for Journal in Brave)

Full work available at URL https://arxiv.org/abs/math/0607070

zbMATH Keywords

large deviationshomozygosityPoisson-Dirichlet distributionGEM representation

Mathematics Subject Classification ID

Large deviations (60F10) Genetics and epigenetics (92D10)

Abstract: The large deviation principle is established for the Poisson--Dirichlet distribution when the parameter $heta$ approaches infinity. The result is then used to study the asymptotic behavior of the homozygosity and the Poisson--Dirichlet distribution with selection. A phase transition occurs depending on the growth rate of the selection intensity. If the selection intensity grows sublinearly in $heta$, then the large deviation rate function is the same as the neutral model; if the selection intensity grows at a linear or greater rate in $heta$, then the large deviation rate function includes an additional term coming from selection. The application of these results to the heterozygote advantage model provides an alternate proof of one of Gillespie's conjectures in [Theoret. Popul. Biol. 55 145--156].

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Cited in

(18)

• Moderate deviations for Poisson-Dirichlet distribution
• Weak limits for the largest subpopulations in Yule processes with high mutation probabilities
• Asymptotic behaviour of an infinitely-many-alleles diffusion with symmetric overdominance
• On Poisson approximations for the Ewens sampling formula when the mutation parameter grows with the sample size
• Stochastic model for cell polarity
• Asymptotic results for the two-parameter Poisson-Dirichlet distribution
• Poisson-Dirichlet distribution with small mutation rate
• Canonical moments and random spectral measures
• Gamma-Dirichlet algebra and applications
• Large deviations associated with Poisson-Dirichlet distribution and Ewens sampling formula
• Large deviations for homozygosity
• Asymptotic behaviour of Poisson-Dirichlet distribution and random energy model
• Asymptotic profile in selection-mutation equations: Gauss versus Cauchy distributions
• Moments of the frequency spectrum of a splitting tree with neutral Poissonian mutations
• Limit theorems associated with the Pitman-Yor process
• A conversation with Don Dawson
• A Central Limit Theorem Associated with the Transformed Two-Parameter Poisson–Dirichlet Distribution
• Functional central limit theorems for stick-breaking priors

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