On the distribution of allele frequencies in a diffusion model

DOI10.1016/0040-5809(79)90031-5zbMATH Open0422.92015OpenAlexW2080635079MaRDI QIDQ1134035FDOQ1134035

Authors: Robert Griffiths 

Publication date: 1979

Published in: Theoretical Population Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/0040-5809(79)90031-5

zbMATH Keywords

diffusion modelneutral modelABO blood group allele frequenciesdistribution of allele frequenciesheterozygote selectiontest of neutrality

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Applications of Brownian motions and diffusion theory (population genetics, absorption problems, etc.) (60J70) Genetics and epigenetics (92D10) Population dynamics (general) (92D25)

Cites Work

• The probability generating functional
• The sampling theory of selectively neutral alleles
• Addendum to a paper of W. Ewens
• The population structure associated with the Ewens sampling formula
• The stationary distribution of the infinitely-many neutral alleles diffusion model
• Variability in the amount of heterozygosity maintained by neutral mutations
• Order Statistics from the Gamma Distribution
• Is the most frequent allele the oldest?
• Homozygosity in three-allele populations

Cited In (28)

• Moderate deviations for Poisson-Dirichlet distribution
• Diffusion processes and the Ewens sampling formula
• Order statistics for jumps of normalised subordinators
• Stochastic model for cell polarity
• Poisson-Dirichlet distribution with small mutation rate
• A generalized model of mutation-selection balance with applications to aging
• Gamma-Dirichlet algebra and applications
• Large deviations associated with Poisson-Dirichlet distribution and Ewens sampling formula
• When can one detect overdominant selection in the infinite-alleles model?
• Homozygosity in three-allele populations
• The two-parameter Poisson-Dirichlet point process
• Line-of-descent and genealogical processes, and their applications in population genetics models
• Two chromosomes with multigene families
• On the Simpson index for the Wright-Fisher process with random selection and immigration
• Analysis of market weights under volatility-stabilized market models
• Orthogonal polynomial kernels and canonical correlations for Dirichlet measures
• Limit theorems associated with the Pitman-Yor process
• Asymptotic behavior of the Poisson-Dirichlet distribution for large mutation rate
• Lines of descent in the diffusion approximation of neutral Wright-Fisher models
• Multivariate Jacobi and Laguerre polynomials, infinite-dimensional extensions, and their probabilistic connections with multivariate Hahn and Meixner polynomials
• A boundary preserving numerical scheme for the Wright-Fisher model
• Gaussian limits associated with the Poisson-Dirichlet distribution and the Ewens sampling formula
• A boundary preserving numerical algorithm for the Wright-Fisher model with mutation
• A Central Limit Theorem Associated with the Transformed Two-Parameter Poisson–Dirichlet Distribution
• Estimating the large mutation parameter of the Ewens sampling formula
• Simulating allele frequencies in a population and the genetic differentiation of populations under mutation pressure
• Random feedback shift registers and the limit distribution for largest cycle lengths
• The non-equilibrium allele frequency spectrum in a Poisson random field framework

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