On the distribution of allele frequencies in a diffusion model

DOI10.1016/0040-5809(79)90031-5MaRDI QIDQ1134035zbMATH OpenOpenAlexFDO

Authors Robert Griffiths

Publication date 1979

Published in Theoretical Population Biology (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/0040-5809(79)90031-5

zbMATH Keywords

ABO blood group allele frequenciesdiffusion modeldistribution of allele frequenciesheterozygote selectionneutral modeltest of neutrality

Mathematics Subject Classification ID

Applications of Brownian motions and diffusion theory (population genetics, absorption problems, etc.) (60J70) Applications of statistics to biology and medical sciences; meta analysis (62P10) Genetics and epigenetics (92D10) Population dynamics (general) (92D25)

Cites work

• Addendum to a paper of W. Ewens
• Homozygosity in three-allele populations
• Is the most frequent allele the oldest?
• Order Statistics from the Gamma Distribution
• The population structure associated with the Ewens sampling formula
• The probability generating functional
• The sampling theory of selectively neutral alleles
• The stationary distribution of the infinitely-many neutral alleles diffusion model
• Variability in the amount of heterozygosity maintained by neutral mutations

Cited in

(33)

• Poisson-Dirichlet distribution with small mutation rate
• Lines of descent in the diffusion approximation of neutral Wright-Fisher models
• Homozygosity in three-allele populations
• Diffusion processes and the Ewens sampling formula
• Simulating allele frequencies in a population and the genetic differentiation of populations under mutation pressure
• When can one detect overdominant selection in the infinite-alleles model?
• Gaussian limits associated with the Poisson-Dirichlet distribution and the Ewens sampling formula
• Orthogonal polynomial kernels and canonical correlations for Dirichlet measures
• Gamma-Dirichlet algebra and applications
• Two chromosomes with multigene families
• The non-equilibrium allele frequency spectrum in a Poisson random field framework
• Order statistics for jumps of normalised subordinators
• A generalized model of mutation-selection balance with applications to aging
• A boundary preserving numerical scheme for the Wright-Fisher model
• Large deviations associated with Poisson-Dirichlet distribution and Ewens sampling formula
• Stochastic model for cell polarity
• A boundary preserving numerical algorithm for the Wright-Fisher model with mutation
• Estimating the large mutation parameter of the Ewens sampling formula
• On the Simpson index for the Wright-Fisher process with random selection and immigration
• Limit theorems associated with the Pitman-Yor process
• A Central Limit Theorem Associated with the Transformed Two-Parameter Poisson–Dirichlet Distribution
• Analysis of market weights under volatility-stabilized market models
• The two-parameter Poisson-Dirichlet point process
• Random feedback shift registers and the limit distribution for largest cycle lengths
• Multivariate Jacobi and Laguerre polynomials, infinite-dimensional extensions, and their probabilistic connections with multivariate Hahn and Meixner polynomials
• Laws of large numbers and central limit theorem for Ewens-Pitman model
• Asymptotics of the allele frequency spectrum and the number of alleles
• Central limit theorems associated with the hierarchical Dirichlet process
• Truncated two-parameter GEM distribution
• Length partition of random multicurves on large genus hyperbolic surfaces
• Line-of-descent and genealogical processes, and their applications in population genetics models
• Moderate deviations for Poisson-Dirichlet distribution
• Asymptotic behavior of the Poisson-Dirichlet distribution for large mutation rate

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