siRNA design. Methods and protocols

DOI10.1007/978-1-62703-119-6MaRDI QIDQ351523zbMATH OpenOpenAlexFDO

Authors

Publication date 5 July 2013

Published in Methods in Molecular Biology (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1007/978-1-62703-119-6

zbMATH Keywords

targetartificial miRNA (amiRNA)asymmetric shorter duplex RNA (asiRNA)bi-functional short hairpin RNA (bi-shRNA)combinatorial RNAidesign of synthetic short RNAsendoribonuclease siRNA (e-siRNA)extended short hairpin RNA (e-shRNA)fork like siRNAgene silencinggene therapyoff target silencing effectplant virusesRNA interferenceRNAiRNAi reagentssecondary small interfering RNAssiRNA designssiRNA screeningsmall interfering RNAstransacting siRNAsvirus immunity

Mathematics Subject Classification ID

Biochemistry, molecular biology (92C40) Systems biology, networks (92C42) Research exposition (monographs, survey articles) pertaining to biology (92-02) Molecular structure (graph-theoretic methods, methods of differential topology, etc.) (92E10)

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Cited in

(4)

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• Selecting effective siRNA target sequences by using Bayes' theorem
• Computational Science – ICCS 2005
• Using radial basis function networks and significance testing to select effective siRNA sequences

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