PANPRSnext

CRANPANPRSnextMaRDI QIDQ5979934

Building PRS Models Based on Summary Statistics of GWAs

Katherine Luo, Garcia Espin Osvaldo

Last update: 17 November 2023

Copyright license: GNU General Public License, version 3.0

Software version identifier: 1.2.0

Description

Shrinkage estimator for polygenic risk prediction (PRS) models based on summary statistics of genome-wide association (GWA) studies. Based upon the methods and original 'PANPRS' package as found in: Chen, Chatterjee, Landi, and Shi (2020) <doi:10.1080/01621459.2020.1764849>.

Cites work

• A Penalized Regression Framework for Building Polygenic Risk Models Based on Summary Statistics From Genome-Wide Association Studies and Incorporating External Information