nlmixr2extra
CRANnlmixr2extraMaRDI QIDQ74524
Nonlinear Mixed Effects Models in Population PK/PD, Extra Support Functions
Bill Denney, Vishal Sarsani, Vipul Mann, Matthew L. Fidler
Last update: 31 January 2024
Copyright license: GNU General Public License
Software version identifier: 2.0.8, 2.0.6, 2.0.7, 2.0.8, 2.0.9
Fit and compare nonlinear mixed-effects models in differential equations with flexible dosing information commonly seen in pharmacokinetics and pharmacodynamics (Almquist, Leander, and Jirstrand 2015 <doi:10.1007/s10928-015-9409-1>). Differential equation solving is by compiled C code provided in the 'rxode2' package (Wang, Hallow, and James 2015 <doi:10.1002/psp4.12052>). This package is for support functions like preconditioned fits <doi:10.1208/s12248-016-9866-5>, boostrap and stepwise covariate selection.
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