dowser
B Cell Receptor Phylogenetics Toolkit
Kenneth Hoehn, Steven H. Kleinstein
Last update: 22 December 2023
Software version identifier: 1.1.0, 1.2.0, 0.1.0, 1.0.0, 1.1.0, 1.2.0, 2.0.0, 2.1.0
Copyright license: GNU Affero General Public License, version 3.0
Provides a set of functions for inferring, visualizing, and analyzing B cell phylogenetic trees. Provides methods to 1) reconstruct unmutated ancestral sequences, 2) build B cell phylogenetic trees using multiple methods, 3) visualize trees with metadata at the tips, 4) reconstruct intermediate sequences, 5) detect biased ancestor-descendant relationships among metadata types Workflow examples available at documentation site (see URL). Citations: Hoehn et al (2022) <doi:10.1371/journal.pcbi.1009885>, Hoehn et al (2021) <doi:10.1101/2021.01.06.425648>.
