Sequential linear rank tests for two-sample censored survival data (Q799060)
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English | Sequential linear rank tests for two-sample censored survival data |
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Sequential linear rank tests for two-sample censored survival data (English)
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1984
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The author provides a general theoretical framework for two-group clinical trials in survival analysis by using martingale methods and stochastic integrals with respect to counting processes. For general patterns of patient-arrival, allocation to treatments and loss to follow- up, it is shown that, under the null-hypothesis of identically distributed lifetimes, the sequentially computed logrank statistic has uncorrelated increments and satisfies a functional limit theorem. The practical applicability to survival testing in randomized clinical trials is discussed.
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censored survival data
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two-group clinical trials
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survival analysis
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martingale methods
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stochastic integrals
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counting processes
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null- hypothesis of identically distributed lifetimes
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logrank statistic
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uncorrelated increments
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functional limit theorem
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randomized clinical trials
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