Testing Hypotheses of Covariate-Adaptive Randomized Clinical Trials

DOI10.1080/01621459.2014.922469MaRDI QIDQ5367390zbMATH OpenOpenAlexFDO

Authors Wei Ma, Lixin Zhang, Feifang Hu

Publication date 13 October 2017

Published in Journal of the American Statistical Association (Search for Journal in Brave)

Full work available at URL https://figshare.com/articles/journal_contribution/Testing_Hypotheses_of_Covariate_Adaptive_Randomized_Clinical_Trials/1473756

zbMATH Keywords

conservative testslinear modelsPocock and Simon's marginal procedurepowerstratified permuted block designtype I error

Mathematics Subject Classification ID

Nonparametric hypothesis testing (62G10) Statistical block designs (62K10) Applications of statistics to biology and medical sciences; meta analysis (62P10)

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Cited in

(44)

• General covariate-adaptive randomization targeting unequal allocation ratio
• Flexible covariate-adjusted exact tests of randomized treatment effects with application to a trial of HIV education
• Multi-arm covariate-adaptive randomization
• Generalized Efron's biased coin design and its theoretical properties
• A theory for testing hypotheses under covariate-adaptive randomization
• Sequential monitoring of covariate-adaptive randomized clinical trials
• SEAMLESS PHASE II/III CLINICAL TRIALS WITH COVARIATE ADAPTIVE RANDOMIZATION
• Robust Tests for Treatment Effect in Survival Analysis under Covariate-Adaptive Randomization
• Statistical inference for covariate-adaptive randomization procedures
• Inference under covariate-adaptive randomization with multiple treatments
• Balancing treatment assignment over all observed covariates in clinical trials
• Estimation accuracy under covariate-adaptive randomization procedures
• Testing interaction between treatment and high‐dimensional covariates in randomized clinical trials
• Validity of tests under covariate-adaptive biased coin randomization and generalized linear models
• Inference in targeted group-sequential covariate-adjusted randomized clinical trials
• Using randomization tests to preserve type I error with response adaptive and covariate adaptive randomization
• Randomization tests in recursive response-adaptive randomization procedures
• Testing hypotheses under covariate-adaptive randomisation and additive models
• Inference after covariate-adaptive randomisation: aspects of methodology and theory
• Comment on ‘Inference after covariate-adaptive randomisation: aspects of methodology and theory’
• Rejoinder on ‘Inference after covariate-adaptive randomization: aspects of methodology and theory’
• Balancing Unobserved Covariates With Covariate-Adaptive Randomized Experiments
• The impact of misclassification on covariate‐adaptive randomized clinical trials
• Hypothesis testing in adaptively sampled data: ART to maximize power beyond \textit{iid }sampling
• Toward Better Practice of Covariate Adjustment in Analyzing Randomized Clinical Trials
• A New and Unified Family of Covariate Adaptive Randomization Procedures and Their Properties
• Regression-adjusted estimation of quantile treatment effects under covariate-adaptive randomizations
• Model-Robust Inference for Clinical Trials that Improve Precision by Stratified Randomization and Covariate Adjustment
• The impacts of unobserved covariates on covariate-adaptive randomized experiments
• The Efficient Covariate-Adaptive Design for high-order balancing of quantitative and qualitative covariates
• Improved estimation of average treatment effects under covariate-adaptive randomization methods
• Minimization in randomized clinical trials
• Regression-based multiple treatment effect estimation under covariate-adaptive randomization
• Subgroup analysis and adaptive experiments crave for debiasing
• The impact of misclassification on covariate-adaptive randomized clinical trials with generalized linear models
• Sample size re-estimation for covariate-adaptive randomized clinical trials
• Regression analysis for covariate-adaptive randomization: a robust and efficient inference perspective
• Statistical inference on the relative risk following covariate-adaptive randomization
• Sample size assessment and interim analysis strategies for survival trial designs with covariate-adaptive randomization
• Sequential monitoring of covariate-adaptive randomized clinical trials with non-parametric approaches
• Validity and power considerations on hypothesis testing under minimization
• Testing heterogeneous treatment effect with quantile regression under covariate-adaptive randomization
• Testing hypotheses of covariate-adaptive randomized clinical trials with time-to-event outcomes under the AFT model
• Covariate-adaptive designs with missing covariates in clinical trials

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