Balancing Unobserved Covariates With Covariate-Adaptive Randomized Experiments

DOI10.1080/01621459.2020.1825450MaRDI QIDQ5885112zbMATH OpenOpenAlexFDO

Authors

Publication date 27 March 2023

Published in Journal of the American Statistical Association (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1080/01621459.2020.1825450

zbMATH Keywords

balancing covariatescorrelationHu and Hu's procedurePocock and Simon's procedurestratified permuted block designunobserved covariates imbalance

Mathematics Subject Classification ID

Nonparametric hypothesis testing (62G10) Statistical block designs (62K10) Response surface designs (62K20) Applications of statistics to biology and medical sciences; meta analysis (62P10)

Recommendations

• Asymptotic properties of covariate-adaptive randomization
• Statistical inference for covariate-adaptive randomization procedures
• Covariate-adaptive designs with missing covariates in clinical trials
• Balancing treatment assignment over all observed covariates in clinical trials
• Handling covariates in the design of clinical trials

Cites work

• A theory for testing hypotheses under covariate-adaptive randomization
• Adaptive clinical trial designs to detect interaction between treatment and a dichotomous biomarker
• Asymptotic properties of covariate-adaptive randomization
• Asymptotic properties of covariate-adjusted response-adaptive designs
• Biased estimates of treatment effect in randomized experiments with nonlinear regressions and omitted covariates
• Forcing a sequential experiment to be balanced
• Handling covariates in the design of clinical trials
• scientific article; zbMATH DE number 1817583 (Why is no real title available?)
• Inference Under Covariate-Adaptive Randomization
• Misspecified proportional hazard models
• Observational studies.
• Randomization, balance, and the validity and efficiency of design-adaptive allocation methods
• Rerandomization to improve covariate balance in experiments
• Sequential rerandomization
• Statistical inference for covariate-adaptive randomization procedures
• Testing Hypotheses of Covariate-Adaptive Randomized Clinical Trials
• The covariate-adaptive biased coin design for balancing clinical trials in the presence of prognostic factors

Cited in

(12)

• Kernel-Based Adaptive Randomization Toward Balance in Continuous and Discrete Covariates
• Balancing treatment assignment over all observed covariates in clinical trials
• Comment on ‘Inference after covariate-adaptive randomisation: aspects of methodology and theory’
• How Well Can Fine Balance Work for Covariate Balancing
• The impacts of unobserved covariates on covariate-adaptive randomized experiments
• Adaptive randomization in network data
• Minimization in randomized clinical trials
• Regression analysis for covariate-adaptive randomization: a robust and efficient inference perspective
• Sequential covariate-adjusted randomization via hierarchically minimizing Mahalanobis distance and marginal imbalance
• The properties of covariate-adaptive randomization procedures with possibly unequal allocation ratio
• Testing heterogeneous treatment effect with quantile regression under covariate-adaptive randomization
• General balance, large data sets and extensions to unbalanced treatment structures

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