Testing homogeneity in a semiparametric two-sample problem
Summary: We study a two-sample homogeneity testing problem, in which one sample comes from a population with density \(f(x)\) and the other is from a mixture population with mixture density \((1 - \lambda)f(x) + \lambda g(x)\). This problem arises naturally from many statistical applications such as tests for partial differential gene expression in microarray studies or genetic studies for gene mutation. Under the semiparametric assumption \(g(x) = f(x)e^{\alpha + \beta x}\), a penalized empirical likelihood ratio test could be constructed, but its implementation is hindered by the fact that there is neither a feasible algorithm for computing the test statistic nor available research results on its theoretical properties. To circumvent these difficulties, we propose an EM test based on the penalized empirical likelihood. We prove that the EM test has a simple chi-square limiting distribution, and we also demonstrate its competitive testing performances by simulations. A real-data example is used to illustrate the proposed methodology.
- EM-test for homogeneity in a two-sample problem with a mixture structure
- Test of homogeneity in semiparametric two-sample density ratio models
- Testing homogeneity in semiparametric mixture case-control models
- Testing homogeneity in a multivariate mixture model
- A partial empirical likelihood based score test under a semiparametric finite mixture model
- Case-control studies with contaminated controls
- Empirical likelihood and general estimating equations
- Empirical likelihood is Bartlett-correctable
- Empirical likelihood ratio confidence intervals for a single functional
- Empirical likelihood ratio confidence regions
- scientific article; zbMATH DE number 5629276 (Why is no real title available?)
- Hypothesis test for normal mixture models: the EM approach
- Hypothesis testing in a mixture case-control model
- Methodology and Algorithms of Empirical Likelihood
- Multivariate logistic compounds
- Non-finite Fisher information and homogeneity: an EM approach
- Penalized likelihood-ratio test for finite mixture models with multinomial observations
- Robust inference strategy in the presence of measurement error
- Testing marginal homogeneity of a continuous bivariate distribution with possibly incomplete paired data
- Semiparametric two-sample admixture components comparison test: the symmetric case
- Test of homogeneity in semiparametric two-sample density ratio models
- scientific article; zbMATH DE number 5629276 (Why is no real title available?)
- Testing homogeneity in semiparametric mixture case-control models
- Using differential variability to increase the power of the homogeneity test in a two-sample problem
- Two‐sample homogeneity testing: A procedure based on comparing distributions of interpoint distances
- A fast score test for generalized mixture models
- EM-test for homogeneity in a two-sample problem with a mixture structure
- A class of pseudolikelihood ratio tests for homogeneity in exponential tilt mixture models
- Using an inequality constraint to increase the power of the homogeneity tests for a two-sample problem with a mixture structure
- Semi-parametric homogeneity test and sample size calculation for a two-sample problem under an inequality constraint
- A partial empirical likelihood based score test under a semiparametric finite mixture model
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