The Effect of Variance Function Estimation on Nonlinear Calibration Inference in Immunoassay Data

DOI10.2307/2533153MaRDI QIDQ4348985zbMATH OpenOpenAlexWikidataFDO

Authors Bruce A. Belanger, Marie Davidian, David M. Giltinan

Publication date 10 August 1997

Published in Biometrics (Search for Journal in Brave)

Full work available at URL https://doi.org/10.2307/2533153

zbMATH Keywords

confidence intervaldrug developmentgeneralized least squaresheteroscedasticityimmunoassaysvariance function estimation

Mathematics Subject Classification ID

General nonlinear regression (62J02) Applications of statistics to biology and medical sciences; meta analysis (62P10)

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Cited in

(12)

• A reliable method of estimating the variance function in immunoassay
• Simultaneous optimal estimates of fixed effects and variance components in the mixed model
• Estimation of variance functions in assays with possibly unequal replication and nonnormal data
• Variance functions and the minimum detectable concentration in assays
• Bootstrap-Adjusted Calibration Confidence Intervals for Immunoassay
• Calibration Inference Based on Multiple Runs of an Immunoassay
• The Effect of Serial Dilution Error on Calibration Inference in Immunoassay
• Calibration for Nonlinear Mixed Effects Models: An Application to the Withdrawal Time Prediction
• Applications of Likelihood Asymptotics for Nonlinear Regression in Herbicide Bioassays
• A robust Bayesian random effects model for nonlinear calibration problems
• A comparison of the variance estimation methods for heteroscedastic nonlinear models
• Simultaneous optimality of LSE and ANOVA estimate in general mixed models

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