Variance functions and the minimum detectable concentration in assays

DOI10.1093/BIOMET/75.3.549MaRDI QIDQ3796602zbMATH OpenOpenAlexFDO

Authors

Publication date 1988

Published in Biometrika (Search for Journal in Brave)

Full work available at URL http://www.lib.ncsu.edu/resolver/1840.4/3795

zbMATH Keywords

Assay analysisasymptotic theorycalibrationgeneralized least-squaresminimum detectable concentrationnonlinear heteroscedastic regression modelpredictionSimulation resultsweighted least-squares

Mathematics Subject Classification ID

Asymptotic properties of parametric estimators (62F12) General nonlinear regression (62J02) Applications of statistics to biology and medical sciences; meta analysis (62P10)

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• Variances are not always nuisance parameters
• FPCA-based method to select optimal sampling schedules that capture between-subject variability in longitudinal studies
• Applied regression analysis bibliography update 1988-89
• A RESTRICTED MAXIMUM LIKELIHOOD PROCEDURE FOR ESTIMATING THE VARIANCE FUNCTION OF AN IMMUNOASSAY
• Inferences of variance function – a parametric robust way
• Conceptual and statistical issues in the validation of analytic dilution assays for pharmaceutical applications
• The Effect of Variance Function Estimation on Nonlinear Calibration Inference in Immunoassay Data
• Bayesian Measures of the Minimum Detectable Concentration of an Immunoassay
• Calibration for Nonlinear Mixed Effects Models: An Application to the Withdrawal Time Prediction
• Applications of Likelihood Asymptotics for Nonlinear Regression in Herbicide Bioassays
• Statistical concepts of capability of detection
• A smooth simultaneous confidence band for conditional variance function
• Assessing the Adequacy of Variance Function in Heteroscedastic Regression Models
• Limits of Quantitation for Laboratory Assays
• A comparison of the variance estimation methods for heteroscedastic nonlinear models
• A diagnostic for heteroscedasticity based on the Spearman rank correlation
• Assessing assay variability of pesticide metabolites in the presence of heavy left-censoring

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