Universality of long-range correlations in expansion-randomization systems

DOI10.1088/1742-5468/2005/10/P10004MaRDI QIDQ4968800zbMATH OpenOpenAlexFDO

Authors Philipp W. Messer, Michael Lässig, P. F. Arndt

Publication date 9 July 2019

Published in Journal of Statistical Mechanics: Theory and Experiment (Search for Journal in Brave)

Full work available at URL https://arxiv.org/abs/q-bio/0509027

zbMATH Keywords

dynamics (theory)models for evolution (theory)mutational and evolutionary processes (theory)

Mathematics Subject Classification ID

Dynamics of disordered systems (random Ising systems, etc.) in time-dependent statistical mechanics (82C44) Problems related to evolution (92D15)

Abstract: We study the stochastic dynamics of sequences evolving by single site mutations, segmental duplications, deletions, and random insertions. These processes are relevant for the evolution of genomic DNA. They define a universality class of non-equilibrium 1D expansion-randomization systems with generic stationary long-range correlations in a regime of growing sequence length. We obtain explicitly the two-point correlation function of the sequence composition and the distribution function of the composition bias in sequences of finite length. The characteristic exponent $chi$ of these quantities is determined by the ratio of two effective rates, which are explicitly calculated for several specific sequence evolution dynamics of the universality class. Depending on the value of $chi$, we find two different scaling regimes, which are distinguished by the detectability of the initial composition bias. All analytic results are accurately verified by numerical simulations. We also discuss the non-stationary build-up and decay of correlations, as well as more complex evolutionary scenarios, where the rates of the processes vary in time. Our findings provide a possible example for the emergence of universality in molecular biology.

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