Wavelet thresholding estimation in a Poissonian interactions model with application to genomic data
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Abstract: This paper deals with the study of dependencies between two given events modeled by point processes. In particular, we focus on the context of DNA to detect favored or avoided distances between two given motifs along a genome suggesting possible interactions at a molecular level. For this, we naturally introduce a so-called reproduction function h that allows to quantify the favored positions of the motifs and which is considered as the intensity of a Poisson process. Our first interest is the estimation of this function h assumed to be well localized. The estimator based on random thresholds achieves an oracle inequality. Then, minimax properties of the estimator on Besov balls are established. Some simulations are provided, allowing the calibration of tuning parameters from a numerical point of view and proving the good practical behavior of our procedure. Finally, our method is applied to the analysis of the influence between gene occurrences along the E. coli genome and occurrences of a motif known to be part of the major promoter sites for this bacterium.
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Cites work
- Adaptive density estimation: A curse of support?
- Adaptive estimation for Hawkes processes; application to genome analysis
- Adaptive estimation of the conditional intensity of marker-dependent counting processes
- Adaptive estimation of the intensity of inhomogeneous Poisson processes via concentration inequalities
- An Introduction to the Theory of Point Processes
- Biorthogonal bases of compactly supported wavelets
- Compound Poisson approximation of word counts in DNA sequences
- Density estimation by wavelet thresholding
- FADO: A Statistical Method to Detect Favored or Avoided Distances between Occurrences of Motifs using the Hawkes' Model
- scientific article; zbMATH DE number 3782254 (Why is no real title available?)
- scientific article; zbMATH DE number 3789676 (Why is no real title available?)
- scientific article; zbMATH DE number 1271137 (Why is no real title available?)
- Ideal spatial adaptation by wavelet shrinkage
- Maximum likelihood estimation of Hawkes' self-exciting point processes
- Multiresolution Approximations and Wavelet Orthonormal Bases of L 2 (R)
- Multiscale Poisson Intensity and Density Estimation
- Near optimal thresholding estimation of a Poisson intensity on the real line
- On minimax density estimation on \(\mathbb R\)
- Spectra of some self-exciting and mutually exciting point processes
- Ten Lectures on Wavelets
Cited in
(7)- Intensity estimation of non-homogeneous Poisson processes from shifted trajectories
- Nonparametric intensity estimation from noisy observations of a Poisson process under unknown error distribution
- Concentration inequalities, counting processes and adaptive statistics
- Adaptive warped kernel estimators
- FADO: A Statistical Method to Detect Favored or Avoided Distances between Occurrences of Motifs using the Hawkes' Model
- A model of Poissonian interactions and detection of dependence
- Concentration inequalities for Poisson point processes with application to adaptive intensity estimation
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