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Using Gaussian graphical models we propose a novel approach to perform pathway analysis using gene expression. Given the structure of a graph (a pathway) we introduce two statistical tests to compare the mean and the concentration matrices between two groups. Specifically, these tests can be performed on the graph and on its connected components (cliques). The package is based on the method described in Massa M.S., Chiogna M., Romualdi C. (2010) <doi:10.1186/1752-0509-4-121>.
Property / description: Using Gaussian graphical models we propose a novel approach to perform pathway analysis using gene expression. Given the structure of a graph (a pathway) we introduce two statistical tests to compare the mean and the concentration matrices between two groups. Specifically, these tests can be performed on the graph and on its connected components (cliques). The package is based on the method described in Massa M.S., Chiogna M., Romualdi C. (2010) <doi:10.1186/1752-0509-4-121>. / rank
 
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Latest revision as of 16:01, 21 March 2024

Gene Set Analysis Exploiting Pathway Topology
Language Label Description Also known as
English
topologyGSA
Gene Set Analysis Exploiting Pathway Topology

    Statements

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    1.4.7
    7 July 2021
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    1.0.2
    10 November 2011
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    1.0.3
    22 December 2011
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    1.0
    24 June 2011
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    1.1.0
    18 July 2012
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    1.2.0
    1 March 2013
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    1.2.1
    26 June 2013
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    1.4.0
    23 October 2013
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    1.4.1
    19 November 2013
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    1.4.2
    12 December 2013
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    1.4.3
    26 March 2014
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    1.4.4
    2 August 2014
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    1.4.5
    9 July 2015
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    1.4.6
    22 September 2016
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    1.5.0
    25 September 2023
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    0 references
    25 September 2023
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    Using Gaussian graphical models we propose a novel approach to perform pathway analysis using gene expression. Given the structure of a graph (a pathway) we introduce two statistical tests to compare the mean and the concentration matrices between two groups. Specifically, these tests can be performed on the graph and on its connected components (cliques). The package is based on the method described in Massa M.S., Chiogna M., Romualdi C. (2010) <doi:10.1186/1752-0509-4-121>.
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    Identifiers