Existence and uniqueness of solutions to a mathematical model of the urine concentrating mechanism (Q1088940): Difference between revisions
From MaRDI portal
Latest revision as of 19:43, 17 June 2024
scientific article
Language | Label | Description | Also known as |
---|---|---|---|
English | Existence and uniqueness of solutions to a mathematical model of the urine concentrating mechanism |
scientific article |
Statements
Existence and uniqueness of solutions to a mathematical model of the urine concentrating mechanism (English)
0 references
1987
0 references
This paper establishes some results for the existence and uniqueness of solutions to a previously published mathematical model of the mammalian urine concentrating mechanism [the author, Distribution of Henle's loops may enhance urine concentrating capability. Biophys. J. 49, 1033-1040 (1986)]. In particular, the contraction mapping principle is used to show that for sufficiently small and sufficiently large values of a positive parameter \(\beta\) there exist unique solutions to the model, whether it be endowed with first-order kinetics or Michaelis-Menten kinetics. Large or small \(\beta\) corresponds to large or small rates of active transport of NaCl from the ascending limbs. The Schauder principle is used to show that there exist solutions to the model for physiologically reasonable reabsorption kinetics, including first-order and Michaelis-Menten kinetics for all values of \(\beta\).
0 references
kidney function
0 references
existence and uniqueness of solutions
0 references
mammalian urine concentrating mechanism
0 references
Henle's loops
0 references
contraction mapping principle
0 references
first-order kinetics
0 references
Michaelis-Menten kinetics
0 references
active transport of NaCl
0 references
Schauder principle
0 references
reabsorption kinetics
0 references
0 references
0 references
0 references
0 references
0 references