Genotypic distribution at the limits to natural and artificial selection with mutation (Q1088946): Difference between revisions

Changes in the genotype distribution under stabilizing selection and long term truncation selection were studied through the cumulants of the density function expressed by Gram-Charlier expansion and Hermite polynomials. Departures from normality were insignificant under additive gene effects, large number of loci and when gene frequencies were not extreme; linkage disequilibrium had only a minor role. At the selection limit, attained mainly through natural selection, skewness and kurtosis were high if mutation was an important cause of genetic variability.