Virus evolution within patients increases pathogenicity

DOI10.1016/j.jtbi.2004.07.016zbMath1442.92033OpenAlexW2039167982WikidataQ45561330 ScholiaQ45561330MaRDI QIDQ776434

Martin A. Nowak, Yoh Iwasa, Franziska Michor

Publication date: 9 July 2020

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jtbi.2004.07.016

zbMATH Keywords

HIVcross-immunityimmune impairmentdirectional evolutionimmune selection

Mathematics Subject Classification ID

Pathology, pathophysiology (92C32)

Related Items (9)

Immune impairment in HIV infection: existence of risky and immunodeficiency thresholds ⋮ HIV evolution and progression of the infection to AIDS ⋮ An HIV infection model based on a vectored immunoprophylaxis experiment ⋮ Frequency dependence and viral diversity imply chaos in an HIV model ⋮ Two optimal mutation rates in obligate pathogens subject to deleterious mutation ⋮ Viral diversity limits immune diversity in asymptomatic phase of HIV infection ⋮ Apoptosis in virus infection dynamics models ⋮ Dynamics of an HBV model with diffusion and delay ⋮ A continuous phenotype space model of RNA virus evolution within a host

Cites Work

• Unnamed Item
• Some basic properties of immune selection
• Diversity and virulence thresholds in AIDS.

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