Interpreting CFSE obtained division histories of B cells in vitro with Smith-Martin and cyton type models

DOI10.1007/s11538-009-9418-6zbMath1173.92011OpenAlexW2075943062WikidataQ33711336 ScholiaQ33711336MaRDI QIDQ1034926

Tim Mosmann, Alan S. Perelson, Edwin Hawkins, Ha Youn Lee, Hulin Wu, Martin S. Zand, Philip D. Hodgkin

Publication date: 9 November 2009

Published in: Bulletin of Mathematical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1007/s11538-009-9418-6

zbMATH Keywords

CFSEcyton modelB cellIL-4Smith-Martin cell cycle modelthymidine labeling

Mathematics Subject Classification ID

Signal detection and filtering (aspects of stochastic processes) (60G35) Cell biology (92C37) Qualitative investigation and simulation of models involving functional-differential equations (34K60)

Related Items (9)

Self-triggered impulsive control of nonlinear time delay systems: application to chemotherapeutic dose-regimen design ⋮ Multi-type branching models to describe cell differentiation programs ⋮ Evaluation of multitype mathematical models for CFSE-labeling experiment data ⋮ Estimation of cell proliferation dynamics using CFSE data ⋮ Mathematical models for CFSE labelled lymphocyte dynamics: asymmetry and time-lag in division ⋮ Parameter identification for model of T cell proliferation in lymphopenia conditions ⋮ Germinal center dynamics during acute and chronic infection ⋮ Quantifying T lymphocyte turnover ⋮ Parameters identification for a model of T cell homeostasis

Cites Work

• Estimating lymphocyte division and death rates from CFSE data
• Bootstrap methods for standard errors, confidence intervals, and other measures of statistical accuracy
• Modeling T cell proliferation and death in vitro based on labeling data: generalizations of the Smith-Martin cell cycle model
• Estimating division and death rates from CFSE data

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