Mechanism-based model of the pharmacokinetics of enfuvirtide, an HIV fusion inhibitor

DOI10.1016/J.JTBI.2007.12.017zbMath1398.92100OpenAlexW2007085886WikidataQ36675928 ScholiaQ36675928MaRDI QIDQ1788684

Utkala Mohanty, Narendra M. Dixit

Publication date: 8 October 2018

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: http://europepmc.org/articles/pmc2396229

zbMATH Keywords

antiretroviral therapyintravenous administrationmultiple dose pharmacokineticssubcutaneous administration

Mathematics Subject Classification ID

Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45) Medical epidemiology (92C60)

Related Items (2)

Modelling the effects of adherence to the HIV fusion inhibitor enfuvirtide ⋮ Resistance to protease inhibitors in a model of HIV-1 infection with impulsive drug effects

Cites Work

• Complex patterns of viral load decay under antiretroviral therapy: influence of pharmacokinetics and intracellular delay
• Drug concentration heterogeneity facilitates the evolution of drug resistance
• INFLUENCE OF DRUG PHARMACOKINETICS ON HIV PATHOGENESIS AND THERAPY
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