Complex patterns of viral load decay under antiretroviral therapy: influence of pharmacokinetics and intracellular delay
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Publication:2187453
DOI10.1016/j.jtbi.2003.09.002zbMath1439.92108OpenAlexW1978430573WikidataQ44668486 ScholiaQ44668486MaRDI QIDQ2187453
Narendra M. Dixit, Alan S. Perelson
Publication date: 3 June 2020
Published in: Journal of Theoretical Biology (Search for Journal in Brave)
Full work available at URL: https://doi.org/10.1016/j.jtbi.2003.09.002
Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45) Medical applications (general) (92C50) Cell biology (92C37)
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Cites Work
- Unnamed Item
- Unnamed Item
- HIV-1 infection and low steady state viral loads
- Optimal viral production
- Influence of delayed viral production on viral dynamics in HIV-1 infected patients
- Modeling HIV dynamics and antiviral response with consideration of time-varying drug exposures, adherence and phenotypic sensitivity
- An age-structured model of HIV infection that allows for variations in the production rate of viral particles and the death rate of productively infected cells
- Dynamics of HIV infection of CD4\(^ +\) T cells
- A model of HIV-1 pathogenesis that includes an intracellular delay
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