An error catastrophe in cancer?

DOI10.1016/J.JTBI.2003.08.018zbMath1439.92070OpenAlexW2038796778WikidataQ52000115 ScholiaQ52000115MaRDI QIDQ2187606

Thomas S. Deisboeck, Ricard V. Solé

Publication date: 3 June 2020

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jtbi.2003.08.018

zbMATH Keywords

phase transitionscancererror thresholdquasispeciestumor progressiongenetic instabilityRNA virusesgenomic instability

Mathematics Subject Classification ID

Genetics and epigenetics (92D10) Pathology, pathophysiology (92C32)

Cites Work

• Unnamed Item

Related Items (15)

Abrupt transitions to tumor extinction: a phenotypic quasispecies model ⋮ The distribution of the quasispecies for a Moran model on the sharp peak landscape ⋮ Characteristic time in quasispecies evolution ⋮ Effect of lethality on the extinction and on the error threshold of quasispecies ⋮ Simulating brain tumor heterogeneity with a multiscale agent-based model: Linking molecular signatures, phenotypes and expansion rate ⋮ Non-neutral role of replicative senescence in tissue homeostasis and tumorigenesis ⋮ Variation approach to error threshold in generic fitness landscape ⋮ Genetic instability and the quasispecies model ⋮ Optimal Control for Anticancer Therapy ⋮ Redundancy-selection trade-off in phenotype-structured populations ⋮ Dynamics and bifurcations in a simple quasispecies model of tumorigenesis ⋮ Cancer stem cells as the engine of unstable tumor progression ⋮ Optimal strategies in the treatment of cancers in the Lotka-Volterra mathematical model of competition ⋮ Lotka-Volterra competition model with a nonmonotone therapy function for finding optimal strategies in the treatment of blood cancers ⋮ Modified quasispecies model: the analysis of a periodic therapy

This page was built for publication: An error catastrophe in cancer?