Practical identifiability of HIV dynamics models

DOI10.1007/S11538-007-9228-7zbMath1245.92055OpenAlexW1998932188WikidataQ51626401 ScholiaQ51626401MaRDI QIDQ2426375

Rodolphe Thiébaut, Daniel Commenges, Jeremie Guedj

Publication date: 22 April 2008

Published in: Bulletin of Mathematical Biology (Search for Journal in Brave)

Full work available at URL: https://www.hal.inserm.fr/inserm-00204273/file/ms0328.pdf

zbMATH Keywords

parameter estimationdesignnonlinear differential equationsFisher information matrix

Mathematics Subject Classification ID

Epidemiology (92D30) Applications of statistics to biology and medical sciences; meta analysis (62P10) Estimation in survival analysis and censored data (62N02)

Related Items (14)

Evaluation of the Fisher information matrix in nonlinear mixed effect models using adaptive Gaussian quadrature ⋮ A nonlinear mixed-effects model for multivariate longitudinal data with dropout with application to HIV disease dynamics ⋮ Mathematical analysis of an HIV infection model including quiescent cells and periodic antiviral therapy ⋮ Model selection and identifiability analysis of HIV and SARS-CoV-2 co-infection model with drug therapy ⋮ Inference in HIV dynamics models via hierarchical likelihood ⋮ A nonlinear mixed-effects model for multivariate longitudinal data with partially observed outcomes with application to HIV disease dynamics ⋮ Joint Modeling of the Clinical Progression and of the Biomarkers' Dynamics Using a Mechanistic Model ⋮ Maximum Likelihood Estimation of Long-Term HIV Dynamic Models and Antiviral Response ⋮ Interval analysis of the HIV dynamics model solution using type-2 fuzzy sets ⋮ Modeling the dynamics of biomarkers during primary HIV infection taking into account the uncertainty of infection date ⋮ Cellular automata with fuzzy parameters in microscopic study of positive HIV individuals ⋮ Mathematical modeling of antigenicity for HIV dynamics ⋮ Score Tests for Exploring Complex Models: Application to HIV Dynamics Models ⋮ A fuzzy delay approach for HIV dynamics using a cellular automaton

Uses Software

• LSODE
• MEMSS
• PATSYM
• HRMSYM
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Cites Work

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• Optimal design in random-effects regression models
• Mixed-Effects Models in S and S-PLUS
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• Identifiability of nonlinear systems with application to HIV/AIDS models
• Statistical methods for HIV dynamic studies in AIDS clinical trials
• Maximum Likelihood Estimation in Dynamical Models of HIV
• Hierarchical Bayesian Methods for Estimation of Parameters in a Longitudinal HIV Dynamic System
• Identification in Parametric Models
• A Basis for the Selection of a Response Surface Design
• Investigating Heterogeneity in Pneumococcal Transmission

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