A Generalized Multihit Dose-Response Model for Low-Dose Extrapolation

DOI10.2307/2530422MaRDI QIDQ3928108zbMATH OpenOpenAlexWikidataFDO

Authors Kamta Rai, John van Ryzin

Publication date 1981

Published in Biometrics (Search for Journal in Brave)

Full work available at URL https://doi.org/10.2307/2530422

zbMATH Keywords

asymptotic normalitystrong consistencymaximum likelihood estimationquantal responsegoodness of fitmultihit modeltoxicity data

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Applications of statistics (62Pxx)

Cited in

(8)

• A two-stage hybrid procedure for estimating an inverse regression function
• The Low Dose Extrapolation Problem: A Review and A New Model
• Extended Models for Quantal Response Data
• The additive damage model: a mathematical model for cellular responses to drug combinations
• Environmental risk assessment model for low dose extrapolation^∗
• A note on a multivariate version of rolle's theorem and uniqueness of maximum likelihood roots
• Dose-response models for time-to-response toxicity data
• A Lagrange-Gamma multihit dose-response model for risk assessment

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