The additive damage model: a mathematical model for cellular responses to drug combinations

DOI10.1016/J.JTBI.2014.04.032zbMATH Open1412.92147OpenAlexW2150498613WikidataQ43067222 ScholiaQ43067222MaRDI QIDQ2415587FDOQ2415587

Authors: Leslie Braziel Jones, T. W. Secomb, Mark W. Dewhirst, Ardith W. El-Kareh 

Publication date: 23 May 2019

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: http://europepmc.org/articles/pmc4367491

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zbMATH Keywords

chemotherapycytotoxicitydose-responsedrug synergycellular pharmacodynamics

Mathematics Subject Classification ID

Medical applications (general) (92C50) Biochemistry, molecular biology (92C40)

Cites Work

• Regression and time series model selection in small samples
• Title not available (Why is that?)
• A Generalized Multihit Dose-Response Model for Low-Dose Extrapolation

Cited In (3)

• A Simple Survival Model for Combined Action of Two Damaging Agents
• Additive damage models for cellular pharmacodynamics of radiation-chemotherapy combinations
• A Generalized Response Surface Model with Varying Relative Potency for Assessing Drug Interaction

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