The additive damage model: a mathematical model for cellular responses to drug combinations

DOI10.1016/J.JTBI.2014.04.032MaRDI QIDQ2415587zbMATH OpenOpenAlexWikidataFDO

Authors Leslie Braziel Jones, T. W. Secomb, Mark W. Dewhirst, Ardith W. El-Kareh

Publication date 23 May 2019

Published in Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL http://europepmc.org/articles/pmc4367491

zbMATH Keywords

chemotherapycytotoxicitydose-responsedrug synergycellular pharmacodynamics

Mathematics Subject Classification ID

Medical applications (general) (92C50) Biochemistry, molecular biology (92C40)

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Cites work

• scientific article; zbMATH DE number 49097 (Why is no real title available?)
• A Generalized Multihit Dose-Response Model for Low-Dose Extrapolation
• Regression and time series model selection in small samples

Cited in

(3)

• A Simple Survival Model for Combined Action of Two Damaging Agents
• Additive damage models for cellular pharmacodynamics of radiation-chemotherapy combinations
• A Generalized Response Surface Model with Varying Relative Potency for Assessing Drug Interaction

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