An improved geometric programming approach for optimization of biochemical systems
Summary: This paper proposes an improved geometric programming approach to address the optimization of biochemical systems. In the proposed method we take advantage of a special and interesting class of nonlinear kinetic models known as generalized mass action (GMA) models. In most situations optimization problems with GMA models are nonconvex and difficult problems to solve for global optimality. To deal with this difficulty, in this work, some transformation strategy is first used to convert the optimization problem with GMA models into an equivalent problem. Then a convexification technique is applied to transform this resulting optimization problem into a series of standard geometric programming problems that can be solved to reach a global solution. Two case studies are presented to demonstrate the advantages of the proposed method in terms of computational efficiency.
- Steady-state optimization of biochemical systems through geometric programming
- Optimization of biochemical systems through mathematical programming: methods and applications
- Optimization of biochemical systems by linear programming and general mass action model representations
- Global optimization of signomial geometric programming problems
- Bi-objective optimization of biochemical systems by linear programming
- A tutorial on geometric programming
- Bi-objective optimization of biochemical systems by linear programming
- Biochemical systems theory and metabolic control theory: I. Fundamental similarities and differences
- Biochemical systems theory and metabolic control theory: II. The role of summation and connectivity relationships
- Comparative characterization of the fermentation pathway of Saccharomyces cerevisiae using biochemical systems theory and metabolic control analysis: Model definition and nomenclature
- Geometric Programming for Communication Systems
- scientific article; zbMATH DE number 3619680 (Why is no real title available?)
- scientific article; zbMATH DE number 1849962 (Why is no real title available?)
- Model based optimization of biochemical systems using multiple objectives: a comparison of several solution strategies
- Optimization of biochemical systems through mathematical programming: methods and applications
- Steady-state optimization of biochemical systems through geometric programming
- Optimization of biochemical systems by linear programming and general mass action model representations
- CMMSE-17: general analytical laws for metabolic pathways
- A neural network approach to solve geometric programs with joint probabilistic constraints
- Steady-state optimization of biochemical systems through geometric programming
- Optimization of biochemical systems through mathematical programming: methods and applications
- A quadratic programming algorithm for steady-state optimization of biochemical systems
- Model based optimization of biochemical systems using multiple objectives: a comparison of several solution strategies
- An algorithm for solving steady-state optimization problem of a class of biochemical systems
- Developing a new approach for (biological) optimal control problems: application to optimization of laccase production with a comparison between response surface methodology and novel geometric procedure
- A neurodynamic approach for joint chance constrained rectangular geometric optimization
- Distributionally robust geometric joint chance-constrained optimization: neurodynamic approaches
This page was built for publication: An improved geometric programming approach for optimization of biochemical systems
Report a bug (only for logged in users!)Click here to report a bug for this page (MaRDI item Q2336665)
